Inventors:
Robert L. Martuza - Marblehead MA, US
Samuel Rabkin - Swampscott MA, US
William Curry - Boston MA, US
Christopher Farrell - Brookline MA, US
Cecile Zaupa - Bassoues, FR
Assignee:
The General Hospital Corporation - Boston MA
International Classification:
C12Q 1/70
Abstract:
Method of stimulating an immune response (e. g. , to treat cancer) include administering to a subject a composition including dendritic cells incubated with (i) oHSV-infected tumor cells or a composition derived therefrom, or (ii) tumor cells plus oHSV, as well as methods of preparing such compositions, are described.