DR. BRADLEY T HYMAN, MD PHD
Neurology at Parkman St, Boston, MA

License number
Massachusetts 70560
Category
Neurology
Type
Neurology
Address
Address
15 Parkman St, Boston, MA 02114
Phone
(617) 726-1728
(617) 724-0287
(617) 726-2894 (Fax)

Professional information

Bradley T Hyman Photo 1

Dr. Bradley T Hyman, Boston MA - MD (Doctor of Medicine)

Specialties:
Neurology
Address:
MASSACHUSETTS GENERAL HOSPITAL
15 Parkman St, Boston 02114
(617) 726-3488 (Phone), (617) 726-7541 (Fax)
MASSACHUSETTS GENERAL HOSPITAL
15 Parkman St STE 835, Boston 02114
(617) 726-5533 (Phone), (617) 726-6991 (Fax)
MASSACHUSETTS GENERAL HOSPITAL
15 Parkman St, Boston 02114
(617) 726-8709 (Phone), (617) 724-3948 (Fax)
Massachusetts General Memory
15 Parkman St STE 835, Boston 02114
(617) 726-1728 (Phone)
Certifications:
Neurology, 1989
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
MASSACHUSETTS GENERAL HOSPITAL
15 Parkman St, Boston 02114
MASSACHUSETTS GENERAL HOSPITAL
15 Parkman St STE 835, Boston 02114
MASSACHUSETTS GENERAL HOSPITAL
15 Parkman St, Boston 02114
Massachusetts General Memory
15 Parkman St STE 835, Boston 02114
Massachusetts General Hospital
55 Fruit St, Boston 02114
Education:
Medical School
Roy J Lucille A Carver College Of Medicine At University Of Iowa
Graduated: 1983
University Iowa
Graduated: 1985
Graduated: 1987
Graduated: 1989


Bradley T Hyman Photo 2

Bradley T Hyman, Boston MA

Specialties:
Neurologist
Address:
15 Parkman St, Boston, MA 02114
Education:
University of Iowa, Roy J. and Lucille A. Carver College of Medicine - Doctor of Medicine
Board certifications:
American Board of Psychiatry and Neurology Certification in Neurology (Psychiatry and Neurology)


Bradley Hyman Photo 3

In Vivo Multiphoton Diagnostic Detection And Imaging Of A Neurodegenerative Disease

US Patent:
7668586, Feb 23, 2010
Filed:
Oct 31, 2001
Appl. No.:
10/001643
Inventors:
Bradley T. Hyman - Charlestown MA, US
Richard Christie - New York NY, US
Brian Bacskai - Charlestown MA, US
Watt W. Webb - Ithaca NY, US
Warren R. Zipfel - Ithaca NY, US
Assignee:
Cornell Research Foundation, Inc. - Ithaca NY
The General Hospital Corporation - Boston MA
International Classification:
A61B 6/00
US Classification:
600473, 600476, 424 96, 356300
Abstract:
The present invention is directed to a method of detecting a neurodegenerative disease in a mammal by activating brain tissue of the mammal by application of radiation under conditions effective to promote a simultaneous multiphoton excitation of the brain tissue and to emit a fluorescence characteristic. The fluorescence characteristic is then compared to a standard fluorescence emitted by exciting healthy brain tissue of the mammal under the same conditions used to carry out the activating step. Brain tissue where the fluorescence characteristic differs from the standard fluorescence is identified as potentially having a neurodegenerative disease. Another aspect of the present invention is directed to a method of producing an image of brain tissue from a mammal by activating brain tissue of a mammal with radiation applied under conditions effective to promote a simultaneous multiphoton excitation of the brain tissue and to produce fluorescence. The fluorescence is then collected to produce an image of the brain tissue.


Bradley Hyman Photo 4

Methods To Monitor Molecule Conformation And Molecule/Molecule Proximity

US Patent:
2005004, Mar 3, 2005
Filed:
Jun 14, 2004
Appl. No.:
10/868756
Inventors:
Bradley Hyman - Charlestown MA, US
Oksana Berezovska - Charlestown MA, US
Brian Bacskai - Charlestown MA, US
Alberto Lleo - Charlestown MA, US
Assignee:
The General Hospital Corporation - Boston MA
International Classification:
C12Q001/68, G01N033/53, G06K009/00
US Classification:
435006000, 435007100, 382128000
Abstract:
The invention relates in part to methods for monitoring the conformation of molecules, include proteins. The methods of the invention are also useful to monitor the distance between two or more molecules, such as the distance between two proteins in a cell. Additionally, the methods of the invention are useful for determining the location of a molecule, e.g. a protein, within a cell or other environment. The invention also relates in part to assays for identifying and testing candidate compounds for modulating molecule conformation and/or molecule interactions.


Bradley Hyman Photo 5

Methods And Compositions For Treating Alzheimer's Disease

US Patent:
2006003, Feb 16, 2006
Filed:
Nov 8, 2004
Appl. No.:
10/983976
Inventors:
Ayae Kinoshita - Sakyo-ku, JP
Christine Von Arnim - Kirchheim, DE
Dudley Strickland - Brookeville MD, US
Bradley Hyman - Charlestown MA, US
International Classification:
A61K 39/395, A61K 38/17, G01N 33/567
US Classification:
424146100, 435007200, 514012000
Abstract:
The present invention relates to the treatment, diagnosis, and prophylactic prevention of Alzheimer's disease. More specifically, the present invention relates to methods and compositions for reducing or preventing the interaction of β-secretase (BACE) with low density lipoprotein receptor related protein (LRP).