Inventors:
The General Hospital Corporation - Boston MA, US
Massachusetts Institute of Technology - Cambridge MA, US
David E. Housman - Newton MA, US
Steven M. Hersch - Jamaica Plain MA, US
Assignee:
Massachusetts Institute of Technology - Cambridge MA
The General Hospital Corporation - Boston MA
International Classification:
C07D 223/02, C07D 217/24, C07C 311/44, C07D 209/80, C07D 333/36, C07D 295/20, C07D 215/40
US Classification:
51421201, 514603, 540604, 544126, 544361, 544363, 546 99, 546171, 548437, 549 69, 564 86
Abstract:
The present invention is based, in part, on assays we conducted that revealed compounds that may be used to treat or prevent diseases characterized by an abnormal or undesirable association of one protein with another.