Inventors:
Whedy Wang - Portola Valley CA, US
Ewa Prokopczuk - Danville CA, US
Luiz Belardinelli - Palo Alto CA, US
Louis Lange - Palo Alto CA, US
Markus Jerling - Bromma, SE
Andrew Wolff - San Francisco CA, US
International Classification:
A61K 31/4965, A61P 9/06
Abstract:
Disclosed are methods for treating patients suffering from cardiovascular diseases comprising administering an intravenous (IV) infusion of ranolazine. In one embodiment, the IV infusion of ranolazine is followed by an orally administered sustained release ranolazine dosage formulation to maintain human ranolazine plasma levels at therapeutic levels in patients.