Inventors:
Scott Panzer - Sunnyvale CA, US
Peter Shapiro - Berkeley CA, US
Steven Banville - Sunnyvale CA, US
Purvi Shah - San Jose CA, US
Michael Chalup - Livingston TX, US
Simon Chang - Sunnyvale CA, US
Alice Chen - San Jose CA, US
Steven D'sa - Toronto Ontario, CA
Stefan Amshey - San Francisco CA, US
Christopher Dahl - Longview TX, US
Tam Dam - San Jose CA, US
Susan Daniels - Mountain View CA, US
Gerard Dufour - Castro Valley CA, US
Vincent Flores - Union City CA, US
Willy Fong - San Francisco CA, US
Lila Greenawalt - San Jose CA, US
Jennifer Jackson - Santa Cruz CA, US
Anissa Jones - San Jose CA, US
Tommy Liu - Daly City CA, US
Ann Roseberry Lincoln - Potomac MD, US
Bruce Rosen - Menlo Park CA, US
Frank Russo - Sunnyvale CA, US
Theresa Stockdreher - Sunnyvale CA, US
Abel Daffo - San Jose CA, US
Rachel Wright - Mountain View CA, US
Pierre Yap - Lafayette CA, US
Jimmy Yu - Fremont CA, US
Diana Bradley - Soquel CA, US
Shawn Bratcher - Mountain View CA, US
Wensheng Chen - Mountain View CA, US
Howard Cohen - Palo Alto CA, US
David Hodgson - Ann Arbor MI, US
Stephen Lincoln - Potomac MD, US
Stuart Jackson - Santa Cruz CA, US
International Classification:
C12Q001/68, C07H021/04
Abstract:
The present invention provides purified disease detection and treatment molecule polynucleotides (mddt). Also encompassed are the polypeptides (MDDT) encoded by mddt. The invention also provides for the use of mddt, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing mddt for the expression of MDDT. The invention additionally provides for the use of isolated and purified MDDT to induce anitbodies and to screen libraries of compounds and the use of anti-MDDT antibodies in diagnostic assays. Also provided are microarrays containing mddt and methods of use.