Inventors:
Ya Wang - Decatur GA, US
Baicheng Hu - Beijing, CN
Walter J. Curran - Atlanta GA, US
Assignee:
EMORY UNIVERSITY - Atlanta GA
International Classification:
A61K 31/7105, A61K 45/06, A61N 5/10, C07H 21/02
US Classification:
514 193, 536 245, 514 44 A, 514 27, 514 34, 4353201, 435366, 600 1
Abstract:
The disclosure relates to microRNAs (miRNAs) for the prophylaxis and/or treatment of neoplasia. The disclosure relates in particular to sequence corresponding to miR2 and the miR-548 family, including precursors, mature forms, fragments, and combinations thereof for the prophylaxis and/or treatment of neoplasias, particularly lung, stomach, and cervical cancer, alone or in combination with additional cancer treatments and therapeutics.