Inventors:
Geoffry L. Curran - Rochester MN, US
Gobinda Sarkar - Rochester MN, US
Joseph F. Poduslo - Rochester MN, US
Robert B. Jenkins - Rochester MN, US
Val J. Lowe - Rochester MN, US
Eric W. Mahlum - Rochester MN, US
Assignee:
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH - Rochester MN
International Classification:
A61K 49/00, C07K 9/00, C07K 14/00, C07K 7/08, C07K 7/06, C07K 5/10, C07K 16/00, A61P 35/00, A61K 38/08, A61K 38/10, A61P 25/00, A61P 25/08, A61P 25/16, A61P 25/28, A61P 31/18, A61K 38/07
US Classification:
424 91, 514 12, 530322, 530324, 530325, 530326, 530327, 530328, 530329, 530330, 530359, 5303913
Abstract:
The peptides described herein can function as carrier peptides. These peptides can associate with (e.g., non-covalently bind) biologically active molecules or imaging agents to transport the biologically active molecules or imaging across the blood-brain barrier. In some cases, such transport may increase the effectiveness of the biological molecules or imaging agents.