Inventors:
Andre Terzic - Rochester MN, US
Timothy Olson - Rochester MN, US
Garvan Kane - Rochester MN, US
International Classification:
C12Q 1/68
Abstract:
This documents relates to potassium channels, SUR2A polypeptides, mutant SUR2A polypeptides, and isolated nucleic acids encoding such polypeptides. In addition, this document provides methods for identifying an individual at risk for cardiac disease, methods for identifying an individual who will not respond to, or who is not responding to, conventional treatment of sepsis and/or hypertension, and methods for screening an individual that has had a poor outcome with catecholamine induction for a deficiency in cardiac Kchanneling. This document also provides methods for treating an individual for a deficiency in cardiac Kchanneling.