Inventors:
Jian Luo - Brisbane CA
Diana M. Fort - Pacifica CA
Donald E. Bierer - Daly City CA
Reimar C. Bruening - San Carlos CA
Steven R. King - Moss Beach CA
Thomas J. Carlson - Oakland CA
Assignee:
Shaman Pharmaceuticals, Inc. - South San Francisco CA
International Classification:
A61K 3578
Abstract:
The use of extracts from Cryptolepis sp. or quindoline alkaloids such quindoline and cryptolepine contained therein as hypoglycemic agents, as well as methods for obtaining the hypoglycemic agents are described. According to a preferred embodiment, the extracts are derived from Cryptolepis sanguinolenta. As hypoglycemic agents, the extracts or quindoline alkaloids such as quindoline or cryptolepine are useful for treating insulin-dependent (type I) and non-insulin-dependent (type II) diabetes.