Inventors:
Dirk Roos - Amsterdam, NL
Alwin A. Voetman - Badhoevedorp, NL
Louis J. Meerhof - Hoogwoud, NL
Bertram Lubin - Oakland CA
Assignee:
Stichting Vrienden Van De Stichting Dr. Karl Landsteiner - Amsterdam
International Classification:
G01N 3353
Abstract:
Granulocytes, particularly neutrophilic granulocytes, also called polymorphonuclear leukocytes (PMN), have been found to retain their immunological properties after enucleation. Moreover, in contrast with normal granulocytes, enucleated granulocytes are stable when stored in frozen condition. The invention relates to the enucleated granulocytes, especially in frozen condition, to a process for preparing the enucleated granulocytes, to a process for assaying antibodies against granulocytes, and to a kit for carrying out the latter process.