Inventors:
Peter Elias - Mill Valley CA, US
Kenneth Feingold - San Rafael CA, US
Joachim Fluhr - San Francisco CA, US
Theodora Mauro - San Francisco CA, US
Martin Behne - San Francisco CA, US
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
A61K038/46, A61K031/685, A61K031/66
US Classification:
424/094600, 514/114000, 514/078000
Abstract:
The integrity, barrier function, cohesion and antimicrobial defense of the stratum corneum pH are improved by acidification, which is achieved by the application of low pH buffers, enzymes, phospholipids or salts with monovalent cations.