STEPHEN FELLER VATNER
Medical Practice in Barnegat Light, NJ

License number
New Jersey 25MA07193500
Issued Date
Feb 13, 2001
Expiration Date
Jun 30, 2017
Category
Medical Examiners
Type
Medical Doctor
Address
Address
Barnegat Light, NJ

Professional information

Stephen Vatner Photo 1

Adenylyl Cyclase Antibodies, Compositions And Uses Thereof

US Patent:
8263401, Sep 11, 2012
Filed:
May 26, 2005
Appl. No.:
11/597065
Inventors:
Stephen F. Vatner - Barnegat Light NJ, US
Dorothy E. Vatner - Barnegat Light NJ, US
Junichi Sadoshima - Berkeley Heights NJ, US
Jayashree Pain - Livingston NJ, US
Assignee:
University of Medicine and Dentistry of New Jersey - Somerset NJ
International Classification:
C12N 5/20, C07K 16/40, C07H 7/00
US Classification:
435326, 435338, 53038826
Abstract:
The invention relates to compositions and methods for diagnosing and treating cardiac conditions and neurodegenerative diseases using antibodies which specifically recognize and bind to the adenylyl cyclase 5 isoform in the heart and brain. These antibodies demonstrate high specificity to the AC5 isoform and do not cross react to any other AC5 isoform. The invention further relates to methods of delivery of drugs to the site of injured tissue using the antibodies of the present invention.