DOROTHY EILEEN VATNER
Medical Practice in Barnegat Light, NJ
License number
New Jersey 25MA07169600
Issued Date
Dec 18, 2000
Expiration Date
Jun 30, 2017
Category
Medical Examiners
Type
Medical Doctor
Address
Address
Barnegat Light, NJ
Professional information
Adenylyl Cyclase Antibodies, Compositions And Uses Thereof
US Patent:
2008027, Nov 6, 2008
Filed:
May 26, 2005
Appl. No.:
11/597065
Inventors:
Stephen F. Vatner - Barnegat Lgt NJ, US
Dorothy E. Vatner - Barnegat Light NJ, US
Junichi Sadoshima - Berkeley Heights NJ, US
Jayashree Pain - Voorhees NJ, US
Dorothy E. Vatner - Barnegat Light NJ, US
Junichi Sadoshima - Berkeley Heights NJ, US
Jayashree Pain - Voorhees NJ, US
Assignee:
UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY - New Brunswick NJ
International Classification:
A61K 39/395, C07K 16/40, C12Q 1/68, A61P 25/00, A61K 31/7088, C12N 5/12
US Classification:
4241331, 5303871, 5303881, 435326, 4241301, 4241461, 435 6, 514 44
Abstract:
The invention relates to compositions and methods for diagnosing and treating cardiac conditions and neurodegenerative diseases using antibodies which specifically recognize and bind to the adenylyl cyclase 5 isoform in the heart and brain. These antibodies demonstrate high specificity to the AC5 isoform and do not cross react to any other AC5 isoform. The invention further relates to methods of delivery of drugs to the site of injured tissue using the antibodies of the present invention.