DR. RUSSEL HUGP PATTERSON, MD
Medical Practice in New York, NY

6379331, Apr 30, 2002

Mar 29, 2001

09/823168

Denise R. Barbut - New York NY
Russel H. Patterson - New York NY

CoAxia, Inc. - Maple Grove MN

A61F 712

604113, 604 28, 607113, 607117

The invention provides a medical device having two elongate catheters, a pump, a refrigeration system, and a manometer. Each catheter has a proximal end, a distal end, a lumen therebetween and communicating with a distal port. The proximal ends of the catheters are connected to the pump and the refrigeration system. The distal ends are adapted for insertion into the subarachnoid space. The cerebral spinal fluid is aspirated from the first catheter to the pump, cooled to below body temperature, and returned to the second catheter. The flow rate of the cerebral spinal fluid is adjusted according the CSF pressure and temperature. Methods of using the devices in treating patients suffering from spinal trauma and undergoing aortic surgery are also disclosed.

6217552, Apr 17, 2001

Apr 7, 1999

9/287969

Denise R. Barbut - New York NY
Russel H. Patterson - New York NY

CoAxia, Inc. - Maple Grove MN

A61F 712

604113

The invention provides a medical device having two elongate catheters, a pump, a refrigeration system, and a manometer. Each catheter has a proximal end, a distal end, a lumen therebetween and communicating with a distal port. The proximal ends of the catheters are connected to the pump and the refrigeration system. The distal ends are adapted for insertion into the subarachnoid space. The cerebral spinal fluid is aspirated from the first catheter to the pump, cooled to below body temperature, and returned to the second catheter. The flow rate of the cerebral spinal fluid is adjusted according the CSF pressure and temperature. Methods of using the devices in treating patients suffering from spinal trauma and undergoing aortic surgery are also disclosed.

2004024, Dec 2, 2004

Jul 2, 2004

10/884124

Denise Barbut - New York NY, US
Russel Patterson - New York NY, US

CoAxia, Inc. - Maple Grove MN

A61F007/12, H05B001/00

604/113000

The invention provides a medical device having a catheter with two lumens and a cooling system. The first lumen has a proximal end and communicates with a port at the distal end. The second lumen has a proximal end and communicates with a side port. The proximal ends of the lumens are connected to the cooling system. The cerebral spinal fluid can be drained from the side port of the first lumen. Methods for cooling the brain to prevent neurologic damage during head trauma or inadequate perfusion are also disclosed.

6758832, Jul 6, 2004

Mar 5, 2002

10/092743

Denise R. Barbut - New York NY
Russel H. Patterson - New York NY

CoAxia, Inc. - Maple Grove MN

A61F 712

604113, 607113, 607117

The invention provides a medical device having two elongate catheters, a pump, and a refrigeration system. Each catheter has a proximal end, a distal end, a lumen therebetween and communicating with a distal port. The proximal ends of the catheters are connected to the pump and the refrigeration system. The distal ends are adapted for insertion into the subarachnoid space. The cerebral spinal fluid is aspirated from the first catheter to the pump, cooled to below body temperature, and returned to the second catheter. The flow rate of the cerebral spinal fluid is adjusted according the CSF pressure and temperature. Also described are methods of using the devices in treating patients suffering from neurologic complications that arise as a result of inadequate cerebral perfusion, such as cardiac arrest, cardiac failure, low cardiac output states, stroke, head injury, cerebral aneurysm surgery, open and closed cardiac surgery and aortic surgery.

6736790, May 18, 2004

Jul 11, 2001

09/904016

Denise R. Barbut - New York NY 10021
Russel H. Patterson - New York NY 10019

A61M 3700

604 613, 604 401, 604 616, 604 614, 604 28, 604509, 604 9601, 60410104, 604113, 600194, 607106

Patients having diminished circulation in the cerebral vasculature as a result of cardiac arrest or from other causes are treated by flowing an oxygenated medium through an arterial access site into the cerebral vasculature and collecting the medium through an access site in the venous site of the cerebral vasculature. In addition to oxygenation, the recirculating blood may also be cooled to hypothermically treat and preserve brain tissue. Isolation and cooling of cerebral vasculature in patients undergoing aortic and other procedures is achieved by internally occluding at least the right common carotid artery above the aortic arch. Blood or other oxygenated medium is perfused through the occluded common carotid artery(ies) and into the arterial cerebral vasculature. Usually, oxygen depleted blood or other medium leaving the cerebral vasculature is collected, oxygenated, and cooled in an extracorporeal circuit so that it may be returned to the patient.

6555057, Apr 29, 2003

Jan 14, 2000

09/483370

Denise R. Barbut - New York NY
Russel H. Patterson - New York NY

CoAxia, Inc. - Maple Grove MN

A61M 136

422 44, 604 613, 604 614, 604113, 435 12, 4352841

Patients having diminished circulation in the cerebral vasculature as a result of stroke or from other causes such as cardiac arrest, shock or head trauma, or aneurysm surgery or aortic surgery, are treated by flowing an oxygenated medium through an arterial access site into the cerebral vasculature and collecting the medium through an access site in the venous site of the cerebral vasculature. Usually, the cold oxygenated medium will comprise autologous blood, and the blood will be recirculated for a time sufficient to permit treatment of the underlying cause of diminished circulation. In addition to oxygenation, the recirculating blood will also be cooled to hypothermically treat and preserve brain tissue. Isolation and cooling of cerebral vasculature in patients undergoing aortic and other procedures is achieved by internally occluding at least the right common carotid artery above the aortic arch. Blood or other oxygenated medium is perfused through the occluded common carotid artery(ies) and into the arterial cerebral vasculature.

2004013, Jul 15, 2004

Dec 23, 2003

10/745844

Denise Barbut - New York NY, US
Russel Patterson - New York NY, US

A61M037/00

604/006130, 604/006140, 604/004010

Patients having diminished circulation in the cerebral vasculature as a result of cardiac arrest or from other causes are treated by flowing an oxygenated medium through an arterial access site into the cerebral vasculature and collecting the medium through an access site in the venous site of the cerebral vasculature. In addition to oxygenation, the recirculating blood may also be cooled to hypothermically treat and preserve brain tissue. Isolation and cooling of cerebral vasculature in patients undergoing aortic and other procedures is achieved by internally occluding at least the right common carotid artery above the aortic arch. Blood or other oxygenated medium is perfused through the occluded common carotid artery(ies) and into the arterial cerebral vasculature. Usually, oxygen depleted blood or other medium leaving the cerebral vasculature is collected, oxygenated, and cooled in an extracorporeal circuit so that it may be returned to the patient.

2003010, Jun 5, 2003

Oct 28, 2002

10/282903

Denise Barbut - New York NY, US
Russel Patterson - New York NY, US

A61N001/362

600/016000, 623/003100

Methods for using blood pumps to treat heart failure are disclosed. The pump is mounted on an interior of a stent, and the stent is releasably mounted on a distal end of a catheter. The distal end of the catheter is inserted into a peripheral artery and advanced to position at a region of interest within the descending aorta, the ascending aorta, or the left ventricle. The stent and the pump are released from the catheter, and the pump is activated to increase blood flow downstream of the pump. The pump can also be positioned in the vena cava or used to treat right-sided heart failure following the insertion of an LVAD, or to improve venous return in patients with varicose veins. Non-stent pumps are described for insertion between the pulmonary vein and aorta, and between the vena cava and pulmonary artery designed for use during cardiac surgery.