ROBERT VITO FARESE, MD
Osteopathic Medicine in San Francisco, CA
License number
California G65728
Category
Osteopathic Medicine
Type
Internal Medicine
License number
California G65728
Category
Osteopathic Medicine
Type
Endocrinology, Diabetes & Metabolism
Address
Address
1001 Potrero Avenue Bldg 30 RM 3501K, San Francisco, CA 94110
Phone
(415) 206-4615
(415) 476-4918 (Fax)
(415) 206-3103
(415) 206-3872 (Fax)
(415) 476-4918 (Fax)
(415) 206-3103
(415) 206-3872 (Fax)
Personal information
See more information about ROBERT VITO FARESE at radaris.comName
Address
Phone
123 Laurel Grove Ave, Greenbrae, CA 94904
123 Laurel Grove Ave, Kentfield, CA 94904
22900 Brdwy Sonoma, Sonoma, CA 95476
5408 Olympic Way, Sacramento, CA 95842
5930 Freeport Blvd, Sacramento, CA 95822
Professional information
Gene-Targeted Animal Model Of Apolipoprotein E4 Domain Interaction And Uses Thereof
US Patent:
2006023, Oct 12, 2006
Filed:
Jun 7, 2006
Appl. No.:
11/449216
Inventors:
Karl Weisgraber - Walnut Creek CA, US
Robert Farese - San Francisco CA, US
Robert Raffai - San Francisco CA, US
Li-Ming Dong - Palo Alto CA, US
Robert Farese - San Francisco CA, US
Robert Raffai - San Francisco CA, US
Li-Ming Dong - Palo Alto CA, US
International Classification:
A01K 67/027, C12N 5/06
US Classification:
800018000, 435354000
Abstract:
The invention provides gene-targeted non-human animals comprising a genetically modified apoE gene encodes a recombinant apoE polypeptide displaying domain interaction. The invention further provides cells isolated from the gene-targeted animals, which cells produce a recombinant apoE polypeptide displaying domain interaction. The invention further provides methods of identifying agents that reduce apoE4 domain interaction, and which are useful to treat apoE4-related neurological and cardiovascular disorders.
Dr. Robert V Farese, San Francisco CA - MD (Doctor of Medicine)
Specialties:
Endocrinology, Diabetes & Metabolism
Address:
1650 Owens St, San Francisco 94158
1001 Potrero Ave SUITE 30, San Francisco 94110
(415) 206-4615 (Phone), (415) 476-4918 (Fax)
1001 Potrero Ave SUITE 30, San Francisco 94110
(415) 206-4615 (Phone), (415) 476-4918 (Fax)
Certifications:
Diabetes, Metabolism & Endocrinology, 1991, Internal Medicine, 1988
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
1650 Owens St, San Francisco 94158
1001 Potrero Ave SUITE 30, San Francisco 94110
San Francisco General Hospital
1001 Potrero Ave, San Francisco 94110
1001 Potrero Ave SUITE 30, San Francisco 94110
San Francisco General Hospital
1001 Potrero Ave, San Francisco 94110
Education:
Medical School
Vanderbilt University
Graduated: 1985
U Colo Affil Hosps
University Of California-San Francisco
Vanderbilt University
Graduated: 1985
U Colo Affil Hosps
University Of California-San Francisco
Polymorphisms In A Diacylglycerol Acyltransferase Gene, And Methods Of Use Thereof
US Patent:
6444427, Sep 3, 2002
Filed:
Jul 11, 2000
Appl. No.:
09/613444
Inventors:
Erwin H. Ludwig - San Anselmo CA
Robert V. Farese - San Francisco CA
Thomas L. Innerarity - Lafayette CA
Sylvaine Cases - Belmont CA
Robert V. Farese - San Francisco CA
Thomas L. Innerarity - Lafayette CA
Sylvaine Cases - Belmont CA
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
C12Q 168
US Classification:
435 6, 435 911, 435 912, 536 231, 536 243, 536 2433
Abstract:
The present invention provides isolated an polynucleotide comprising a polymorphic nucleotide sequence from a diacylglycerol acyltransferase (DGAT) gene, wherein at least one a polymorphism is associated with a condition relating to DGAT activity. The invention further provides diagnostic assays for detecting the presence in a nucleic acid sample of a polymorphism in a DGAT gene that is associated with a condition relating to DGAT activity, and for detecting a propensity to develop a condition associated with DGAT activity. The invention further provides treatment methods.
Mono-And Diacylglycerol Acyltransferases And Methods Of Use Thereof
US Patent:
2003016, Aug 28, 2003
Filed:
Oct 31, 2002
Appl. No.:
10/286581
Inventors:
Sylvaine Cases - Belmont CA, US
Scot Stone - Fairfield CA, US
Ping Zhou - Walnut Creek CA, US
Robert Farese - San Francisco CA, US
Chi-Liang Yen - San Francisco CA, US
Scot Stone - Fairfield CA, US
Ping Zhou - Walnut Creek CA, US
Robert Farese - San Francisco CA, US
Chi-Liang Yen - San Francisco CA, US
International Classification:
A61K039/395, C07H021/04, C12N009/10, C12P021/02, C12N005/06, C07K016/40
US Classification:
424/146100, 435/193000, 435/069100, 435/320100, 435/325000, 536/023200, 530/388260
Abstract:
Nucleic acid compositions encoding polypeptide products with diglyceride acyltransferase and/or monoacylglycerol acyltransferase activity, as well as the polypeptide products encoded thereby, i.e., mammalian DGAT2, MGAT1, or MGAT2 polypeptide products, and methods for producing the same, are provided. Also provided are: methods and compositions for modulating DGAT2, MGAT1, or MGAT2 activity; DGAT2, MGAT1, or MGAT2 transgenic cells, animals and plants, as well as methods for their preparation; and methods for making diglyceride, diglyceride compositions, triglycerides and triglyceride compositions, as well as the compositions produced by these methods. The subject methods and compositions find use in a variety of different applications, including research, medicine, agriculture and industry applications.
Plant Diacylglycerol O-Acyltransferase And Uses Thereof
US Patent:
2003007, Apr 17, 2003
Filed:
Aug 15, 2002
Appl. No.:
10/223076
Inventors:
Robert Farese - San Francisco CA, US
Sylvaine Cases - Belmont CA, US
Sylvaine Cases - Belmont CA, US
International Classification:
A01H005/00, C07H021/04, C12N009/06, C12N009/10, C12N015/82, C12N005/04
US Classification:
800/281000, 435/069100, 435/191000, 435/193000, 435/320100, 435/419000, 536/023200
Abstract:
Plant nucleic acid compositions encoding polypeptide products with diacylglyceride acyltransferase (DGAT) activity, as well as the polypeptide products encoded thereby and methods for producing the same, are provided. Methods and compositions for modulating DGAT activity in a plant, particularly DGAT activity in plant seeds, and transgenic plants with altered DGAT activity are provided. Such plants and seeds are useful in the production of human food and animal feedstuff, and have several other industrial applications. Also provided are methods for making triglycerides and triglyceride compositions, as well as the compositions produced by these methods. The subject methods and compositions find use in a variety of different applications, including research, medicine, agriculture and industry.
Methods And Compositions For Modulating Carbohydrate Metabolism
US Patent:
2007012, May 31, 2007
Filed:
Dec 12, 2006
Appl. No.:
11/609810
Inventors:
Robert Farese - San Francisco CA, US
Hubert Chen - San Francisco CA, US
Hubert Chen - San Francisco CA, US
International Classification:
A61K 38/22
US Classification:
514012000
Abstract:
Methods and compositions for modulating carbohydrate metabolism in a host are provided. In the subject methods, diacylglycerol acyltransferase (DGAT) activity (specifically DGAT1 activity) is modulated, e.g., reduced or enhanced, to achieve a desired insulin and/or leptin sensitivity, thereby modulating carbohydrate metabolism, e.g., increasing or decreasing blood glucose levels, glucose uptake into cells and assimilation into glycogen. Also provided are pharmaceutical compositions for practicing the subject methods. The subject methods and compositions find use in a variety of applications, including the treatment of hosts suffering conditions associated with abnormal carbohydrate metabolism, such as obesity or diabetes.
Diacylglycerol O-Acyltransferase
US Patent:
2003007, Apr 17, 2003
Filed:
Oct 16, 2002
Appl. No.:
10/273438
Inventors:
Robert Farese - San Francisco CA, US
Sylvaine Cases - Belmont CA, US
Steven Smith - San Francisco CA, US
Sandra Erickson - Mountain View CA, US
Sylvaine Cases - Belmont CA, US
Steven Smith - San Francisco CA, US
Sandra Erickson - Mountain View CA, US
International Classification:
G01N033/53, A01K067/027, A61K039/395, C12N005/06, C07K016/40
US Classification:
424/146100, 530/388260, 435/338000, 435/007100
Abstract:
Nucleic acid compositions encoding polypeptide products with diglyceride acyltransferase activity, as well as the polypeptide products encoded thereby and methods for producing the same, are provided. The subject polypeptide and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications, as well as in treatment therapies and in the production of triacylglycerols.
Methods And Compositions For Modulating Carbohydrate Metabolism
US Patent:
2003015, Aug 14, 2003
Filed:
Nov 5, 2002
Appl. No.:
10/289172
Inventors:
Robert Farese - San Francisco CA, US
Hubert Chen - San Francisco CA, US
Hubert Chen - San Francisco CA, US
International Classification:
A01K067/027, A61K038/28, A61K038/17
US Classification:
800/018000, 514/002000, 514/003000
Abstract:
Methods and compositions for modulating carbohydrate metabolism in a host are provided. In the subject methods, diacylglycerol acyltransferase (DGAT) activity (specifically DGAT1 activity) is modulated, e.g., reduced or enhanced, to achieve a desired insulin and/or leptin sensitivity, thereby modulating carbohydrate metabolism, e.g., increasing or decreasing blood glucose levels, glucose uptake into cells and assimilation into glycogen. Also provided are pharmaceutical compositions for practicing the subject methods. The subject methods and compositions find use in a variety of applications, including the treatment of hosts suffering conditions associated with abnormal carbohydrate metabolism, such as obesity or diabetes.
Alpha-Tocopherol Transfer Protein Knockout Animals
US Patent:
2002017, Nov 14, 2002
Filed:
Nov 1, 2001
Appl. No.:
10/001278
Inventors:
Robert Farese - San Francisco CA, US
Yuko Terasawa - Campbell CA, US
Maret Traber - Corvallis OR, US
Yuko Terasawa - Campbell CA, US
Maret Traber - Corvallis OR, US
Assignee:
The Regents of the University of California
International Classification:
A01K067/027, C12Q001/68, C12N009/10
US Classification:
800/014000, 800/015000, 800/016000, 800/017000, 800/018000, 435/006000, 435/320100, 435/193000
Abstract:
This invention provides knockout animals comprising a disruption in one or both alleles of the gene encoding alpha-tocopherol transfer protein (TTP). The knockout animals provide good model systems for atherosclerosis.
Diacylglycerol O-Acyltransferase 2Alpha (Dgat2Alpha)
US Patent:
2002011, Aug 29, 2002
Filed:
Feb 26, 2001
Appl. No.:
09/794715
Inventors:
Sylvaine Cases - Belmont CA, US
Robert Farese - San Francisco CA, US
Scot Stone - Fairfield CA, US
Ping Zhou - Walnut Creek CA, US
Robert Farese - San Francisco CA, US
Scot Stone - Fairfield CA, US
Ping Zhou - Walnut Creek CA, US
International Classification:
A61K038/52, A61K039/395, C07H021/04, C12P021/02, C12N009/10, C12N005/06
US Classification:
424/094500, 435/069100, 435/193000, 435/325000, 435/320100, 536/023200
Abstract:
Nucleic acid compositions encoding mammalian DGAT2 polypeptide products with diglyceride acyltransferase activity, as well as the mammalian DGAT2 polypeptide products encoded thereby and methods for producing the same, are provided. The subject DGAT2 polypeptide and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications, as well as in treatment therapies and in the production of triacylglycerols.