RICHARD J COHEN, M.D.
Osteopathic Medicine at Monadnock Rd, Boston, MA

6308093, Oct 23, 2001

Oct 7, 1999

9/413969

Antonis A. Armoundas - Cambridge MA
Andrew B. Feldman - Newport RI
Derin A. Sherman - Lincoln MA
Richard J. Cohen - Chestnut Hill MA

Massachusetts Institute of Technology - Cambridge MA

A61B 500

600509

This invention involves method and apparatus for guiding ablative therapy of abnormal biological electrical excitation. In particular, it is designed for treatment of cardiac arrhythmias. In the method of this invention electrical signals are acquired from passive electrodes, and an inverse dipole method is used to identify the site of origin of an arrhytmia. The location of the tip of the ablation catheter is similarly localized from signals acquired from the passive electrodes while electrical energy is delivered to the tip of the catheter. The catheter tip is then guided to the site of origin of the arrhythmia, and ablative radio frequency energy is delivered to its tip to ablate the site.

2011013, Jun 9, 2011

Jan 2, 2009

12/319158

Harry Lee - Boston MA, US
Allan Foreman - Epping NH, US
Wolfgang Daum - Groton MA, US
Richard Cohen - Chestnut Hill MA, US
Jean Gotman - Westmount, CA
Andrew James Cole - Lincoln MA, US

A61N 1/37

607 62

Disclosed are medical devices for the prevention and/or treatment of neurological disorders via electrical stimulation, and methods related thereto. The devices may also be utilized to detect disorders before the prevention or treatment of a neurological disorder. These devices are minimally or non-invasive. The present medical devices comprise various components, which include electrodes and control electronics. The electrodes are targeting electrodes constructed from ring type structures or virtually connected disc type arrays. The electrodes are located entirely outside the skull. The present medical devices also comprise one or more subsystems, a control system, a battery unit, and wires connecting the one or more subsystems. These devices may also be used for acute seizure control.

7815578, Oct 19, 2010

Sep 22, 2003

10/667956

Richard J. Cohen - Chestnut Hill MA, US
Ramakrishna Mukkamala - Lansing MI, US
Derin A. Sherman - Cedar Rapids IA, US

Massachusetts Institute of Technology - Cambridge MA
Board of Trustees of Michigan State University - East Lansing MI

A61B 5/02

600526, 600500

The present invention provides methods and apparatus for determining a dynamical property of the systemic or pulmonary arterial tree using long time scale information, i. e. , information obtained from measurements over time scales greater than a single cardiac cycle. In one aspect, the invention provides a method and apparatus for monitoring cardiac output (CO) from a single blood pressure signal measurement obtained at any site in the systemic or pulmonary arterial tree or from any related measurement including, for example, fingertip photoplethysmography. According to the method the time constant of the arterial tree, defined to be the product of the total peripheral resistance (TPR) and the nearly constant arterial compliance, is determined by analyzing the long time scale variations (greater than a single cardiac cycle) in any of these blood pressure signals. Then, according to Ohm's law, a value proportional to CO may be determined from the ratio of the blood pressure signal to the estimated time constant. The proportional CO values derived from this method may be calibrated to absolute CO, if desired, with a single, absolute measure of CO (e. g.

7336995, Feb 26, 2008

Nov 19, 2002

10/299415

Antonis A. Armoundas - Cambridge MA, US
Richard J. Cohen - Chestnut Hill MA, US

Massachusetts Institute of Technology - Cambridge MA

A61N 1/362

607 9, 600513

Method and apparatus for preventing heart rhythm disturbances by recording cardiac electrical activity, measuring beat-to-beat variability in the morphology of electrocardiographic waveforms, and using the measured beat-to-beat variability to control the delivery of drug therapy and electrical impulses to the heart.

2010011, May 6, 2010

Oct 11, 2007

12/445139

Richard J. Cohen - Chestnut Hill MA, US
Danilo Scepanovic - Cambridge MA, US

Massachusetts Institute of Technology - Cambridge MA

A61B 5/02

600301

Method for determining physiological stress. One or more physiologic signals in a subject is detected. The one or more physiologic signals are processed to obtain one or more processed signals. The subject's stress level is estimated from the one or more processed signals. The one or more physiological signals may include the electrocardiogram, instantaneous lung volume or other signal reflecting respiratory activity, or the arterial blood pressure or other signal reflecting cardiovascular activity.