REBECCA GRAY WELLS
Medical Practice in Penn Wynne, PA
License number
Pennsylvania MD419756
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
Penn Wynne, PA 19096
Personal information
See more information about REBECCA GRAY WELLS at radaris.comName
Address
Phone
350 Rr 1 POB 350, Lawrenceville, PA 16929
Professional information
T1 Rho Magnetic Resonance Imaging For Staging Of Hepatic Fibrosis
US Patent:
2011002, Feb 3, 2011
Filed:
Jul 30, 2010
Appl. No.:
12/846920
Inventors:
DANIA DAYE - PHILADELPHIA PA, US
RAVINDER REDDY - GLADWYNE PA, US
REBECCA WELLS - WYNNEWOOD PA, US
RAVINDER REDDY - GLADWYNE PA, US
REBECCA WELLS - WYNNEWOOD PA, US
International Classification:
A61B 5/055
US Classification:
600410
Abstract:
Methods for diagnosis of fibrotic diseases, staging of fibrotic diseases and monitoring treatment of fibrosis. The presence of fibrotic tissue is detected. First, a Trelaxation time of tissue is determined using magnetic resonance imaging. The determined Trelaxation time is then compared to a baseline Trelaxation time indicative of healthy tissue, and the presence of fibrotic tissue is then determined based on results of said comparison step. To determine a stage of fibrosis, a Trelaxation time of tissue is determined and compared to one or more calibrated Trelaxation times indicative of one or more stages of fibrosis, and the stage of fibrosis is determined based on results of said comparison step. The proposed technology offers a non-invasive MRI technique based on Tcontrast that is sensitive enough to detect small changes of ECM hepatic protein concentration and architecture in all stages of hepatic fibrosis.