Inventors:
Jerome M. Schulman - New York NY
Raj K. Goyal - Boston MA
International Classification:
A61K 31415, C07D23360
Abstract:
Compounds useful as cholinergic drugs are disclosed which have the formula A--B and pharmaceutically acceptable salts thereof having the formula [(A--B)Q]+. sub. q M. sup. -q wherein M is a pharmaceutically acceptable anion, Q is a proton or lower alkylating group, q is as integer from 1 to 3, A is a saturated or unsaturated five- or six-membered heterocyclic moiety and B is a saturated or unsaturated five-memebered heterocyclic moiety wherein R. sup. 1 and R. sup. 2 are each independently hydrogen, halo, branched or straight-chain C. sub. 1 -C. sub. 6 alkyl, branched or straight-chain C. sub. 1 -C. sub. 6 haloalkyl, branched or straight-chain C. sub. 1 -C. sub. 6 alkoxy, hydroxyl, keto or aryl; Y is --N. dbd. or ##STR1## Z is --N. dbd. , ##STR2## --O--, --S--, ##STR3## and R. sup. 3, R. sup. 4 and R. sup.