EUGENE CHAN
Osteopathic Medicine at Francis St, Boston, MA
License number
Massachusetts 233011
Category
Osteopathic Medicine
Type
Internal Medicine
Address
Address
75 Francis St, Boston, MA 02115
Phone
(617) 525-6841
Personal information
See more information about EUGENE CHAN at radaris.comName
Address
Phone
47 Tuttle St, Dorchester, MA 02125
8 Sharon St, Tewksbury, MA 01876
116 Charles St, Boston, MA 02114
25 Beaver St, Boston, MA 02108
Organization information
See more information about EUGENE CHAN at bizstanding.comEugene Chan MD
75 Francis St, Boston, MA 02115
Industry:
Internist
Phone:
(617) 525-6841 (Phone)
Eugene Yan-Ho Chan
Professional information
Methods Of Analyzing Polymers Using A Spatial Network Of Fluorophores And Fluorescence Resonance Energy Transfer
US Patent:
6772070, Aug 3, 2004
Filed:
Feb 15, 2001
Appl. No.:
09/783930
Inventors:
Rudolf Gilmanshin - Waltham MA
Eugene Y Chan - Boston MA
Eugene Y Chan - Boston MA
Assignee:
U.S. Genomics, Inc. - Woburn MA
International Classification:
G06F 1900
US Classification:
702 19, 435 6
Abstract:
The present invention relates to methods and apparatuses for analyzing molecules, particularly polymers, and molecular complexes with extended or rod-like conformations. In particular, the methods and apparatuses are used to identify repetitive information in molecules or molecular ensembles, which is interpreted using an autocorrelation function in order to determine structural information about the molecules. The methods and apparatuses of the invention are used for, inter alia, determining the sequence of a nucleic acid, determining the degree of identity of two polymers, determining the spatial separation of specific sites within a polymer, determining the length of a polymer, and determining the velocity with which a molecule penetrates a biological membrane.
Methods Of Analyzing Polymers Using Ordered Label Strategies
US Patent:
6403311, Jun 11, 2002
Filed:
Aug 13, 1999
Appl. No.:
09/374415
Inventors:
Eugene Y. Chan - Boston MA
Assignee:
US Genomics - Woburn MA
International Classification:
C12Q 168
US Classification:
435 6, 435375, 435 5, 2041828, 935 77, 935 78, 436 94, 548416, 549382, 546 33
Abstract:
The invention relates to methods and products for analyzing polymers. The polymers are analyzed by reconstructing sequence information from population data sets. The data sets include information about polymer dependent impulses arising from the polymers. The invention is also a method for linearly analyzing polymers by assessing the intensity of a signal arising from the polymer. The signal is generated as units and/or units specific markers pass a fixed station. The quantitative intensity of the signal is proportional to the number of units and/or unit specific markers giving rise to the signal.
Eugene Chan, Boston MA
Specialties:
Internist
Address:
75 Francis St, Boston, MA 02115
Methods Of Analyzing Polymers Using A Spatial Network Of Fluorophores And Fluorescence Resonance Energy Transfer
US Patent:
6263286, Jul 17, 2001
Filed:
Aug 13, 1999
Appl. No.:
9/374902
Inventors:
Rudolf Gilmanshin - Waltham MA
Eugene Y. Chan - Boston MA
Eugene Y. Chan - Boston MA
Assignee:
U.S. Genomics, Inc. - Woburn MA
International Classification:
G01N 3348, C12Q 168
US Classification:
702 19
Abstract:
The present invention relates to methods and apparatuses for analyzing molecules, particularly polymers, and molecular complexes with extended or rod-like conformations. In particular, the methods and apparatuses are used to identify repetitive information in molecules or molecular ensembles, which is interpreted using an autocorrelation function in order to determine structural information about the molecules. The methods and apparatuses of the invention are used for, inter alia, determining the sequence of a nucleic acid, determining the degree of identity of two polymers, determining the spatial separation of specific sites within a polymer, determining the length of a polymer, and determining the velocity with which a molecule penetrates a biological membrane.
Microfluidic Passive Mixing Chip
US Patent:
2013026, Oct 3, 2013
Filed:
Dec 14, 2011
Appl. No.:
13/374157
Inventors:
Eugene Y. Chan - Boston MA, US
Moon Z. Chan - Boston MA, US
Moon Z. Chan - Boston MA, US
International Classification:
G01N 1/38
US Classification:
436174, 422502, 422 681
Abstract:
An improved device and method for passive mixing of fluids is described, and the use of the device in clinical diagnostic procedures. The mixer provides thorough mixing of a sample of blood or other fluid with an assay material, such as a diluent or a component of an assay system, in a closed system with a low and limited pressure drop. Sample size is small, typically 5 to 300 microliters. Mixing is accomplished by a combination of rotational vortex mixing due to a fluid stream coming tangent to a drain, and either or both of a second vortex mixer of opposite handedness, and a Dean mixer. Combinations of these techniques reliably provide complete mixing at low pressure drop. In a preferred usage, the microfluidic system can run a diluent continuously and inject samples at intervals, to facilitate automatic data processing of optical or other signatures of the well-mixed stream.
Methods Of Analyzing Polymers Using Ordered Label Strategies
US Patent:
2002011, Aug 15, 2002
Filed:
Aug 13, 2001
Appl. No.:
09/928668
Inventors:
Eugene Chan - Boston MA, US
Assignee:
US Genomics, Inc. - Woburn MA
International Classification:
C12Q001/68, G01N033/53, C07H021/04
US Classification:
435/006000, 435/007100, 536/024300
Abstract:
The invention relates to methods and products for analyzing polymers. The polymers are analyzed by reconstructing sequence information from population data sets. The data sets include information about polymer dependent impulses arising from the polymers. The invention is also a method for linearly analyzing polymers by assessing the intensity of a signal arising from the polymer. The signal is generated as units and/or units specific markers pass a fixed station. The quantitative intensity of the signal is proportional to the number of units and/or unit specific markers giving rise to the signal.
Methods And Apparatuses For Stretching Polymers
US Patent:
8518705, Aug 27, 2013
Filed:
Feb 10, 2004
Appl. No.:
10/775599
Inventors:
Eugene Y. Chan - Boston MA, US
Lance C. Gleich - Somerville MA, US
Parris S. Wellman - Somerville MA, US
Lance C. Gleich - Somerville MA, US
Parris S. Wellman - Somerville MA, US
Assignee:
PathoGenetix, Inc. - Woburn MA
International Classification:
B01L 3/00
US Classification:
436 94, 422502, 422503, 436 86
Abstract:
The present invention provides structures and methods that allow polymers of any length, including nucleic acids containing entire genomes, to be stretched into a long, linear conformation for further analysis. The present invention also provides structures and methods for selecting and stretching polymers based on their lengths. Polymers are loaded into a device and run through the structures. Stretching is achieved by, e. g. , applying shear forces as the polymer passes through the structures, placing obstacles in the path of the polymer, or a combination thereof. Since multiple molecules may be stretched in succession, extremely high throughput screening, e. g. , screening of more than one molecule per second, is achieved.
Flow Based Clinical Analysis
US Patent:
2012021, Aug 23, 2012
Filed:
Jan 6, 2012
Appl. No.:
13/374683
Inventors:
Eugene Y. Chan - Boston MA, US
International Classification:
C12M 1/34, G01N 33/50, G01N 27/22, G01N 21/47, G01N 27/06, G01N 27/02, C12M 1/40, G01N 21/64
US Classification:
4352872, 4352887, 422 681, 422 8208, 422 8205, 422 8202, 422 8201, 4352871
Abstract:
Values of clinical properties are normally measured by taking a sample from a patient, mixing an aliquot with a reagent, placing the mixture into a selected instrument, and measuring a property. If another property is required, another measurement sequence must be created. This can be efficient on a large scale, for example in a centralized laboratory, but is inefficient on a small scale. It is shown that by using measurement systems based on manipulation of flowing streams, clinical assays can be performed by a hand held device. This flow based system allows complex assays to be performed in remote locations with automated portable instruments that can be flexible enough to conduct a wide variety of assays.
Multicoded Analytical Nanostrips
US Patent:
2012019, Aug 2, 2012
Filed:
Jan 30, 2012
Appl. No.:
13/361914
Inventors:
Eugene Y. Chan - Boston MA, US
Moon Z. Chan - Boston MA, US
Moon Z. Chan - Boston MA, US
International Classification:
G01N 21/64
US Classification:
436501, 422 69
Abstract:
Analytical nanostrips for clinical analysis are improved by using multifunctional coding (“multicoding”) to allow simultaneous identification of the particular assay, the value of the assayed analyte, and a calibration of the analyte. The multicoding layout on the nanostrip minimizes the number of zones that are required for a given assay. Moreover, the nanostrip can be scanned in real time during flow of the nanostrip through a detection beam. This both simplifies the assay and allows for alternative means of coding.
Methods And Products For Analyzing Polymers
US Patent:
2012021, Aug 30, 2012
Filed:
Mar 28, 2012
Appl. No.:
13/432959
Inventors:
Eugene Y. Chan - Boston MA, US
Assignee:
LIFE TECHNOLOGIES CORPORATION - Carlsbad CA
International Classification:
G01N 27/447
US Classification:
204451
Abstract:
Methods and products for analyzing polymers are provided. The methods include methods for determining various other structural properties of the polymers.