DR. NIKOLAUS GRAVENSTEIN, MD
Anesthesiologist Assistant at Archer Rd, Gainesville, FL

5101825, Apr 7, 1992

Jun 20, 1989

7/368636

Dietrich Gravenstein - Gainesville FL
J. E. W. Beneken - Helmond, NL
Samsun Lampotang - Gainesville FL
Nikolaus Gravenstein - Gainesville FL
Michael A. Brooks - Gainesville FL
Gordon L. Gibby - Gainesville FL
Robert J. Atwater - Gainesville FL

BlackBox, Inc. - Gainesville FL

A61B 500

128633

Described here are a novel means and device for noninvasively quantifying important blood constituents. Total hemoglobin, arterial oxygen content, hematocrit, and other parameters can all be determined quickly and easily without the need for skin puncture or lengthy laboratory analysis. The invention described here concerns the simultaneous measurement of volume changes and changes in the mass of either oxyhemoglobin, total hemoglobin, or reduced hemoglobin. The data obtained by these measurements is used to quantify the parameters of interest.

5156159, Oct 20, 1992

Apr 9, 1990

7/505689

Samsun Lampotang - Gainesville FL
Joachim S. Gravenstein - Gainesville FL
Nikolaus Gravenstein - Gainesville FL
Michael J. Banner - Gainesville FL
Dietrich Gravenstein - Gainesville FL

University of Florida - Gainesville FL

A61M 1600

128719

A diagnostic monitor checks the carbon dioxide (CO. sub. 2) content of a gas exiting a patient during endotracheal or esophageal intubation. A plurality of composition portions substantially change color in response to exposure to the carbon dioxide. The composition portions change color in response to different times of exposure to carbon dioxide. A magnifying or condensing lens may be positioned on the monitor to enhance viewing of the color change. The monitor may advantageously be made part of an intubation system through which the gases from a patient exit the patient. The differences in time of exposure needed to cause the color change may be accomplished by using semipermeable membranes having differing thicknesses, CO. sub. 2 permeabilities, and/or surface areas with each membrane corresponding to a particular one of the composition portions. An arrangement is provided whereby the monitor is automatically activated by the normal assembly steps of a patient breathing circuit.

2006015, Jul 13, 2006

Jul 15, 2005

11/182706

Samsun Lampotang - Gainesville FL, US
Nikolaus Gravenstein - Gainesville FL, US

UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. - Gainesville FL

A61M 15/00, A61M 15/08

128203120, 128203140, 128203220

An apparatus and method for titrating the oxygen content delivered to a patient via an open delivery system and reduce fire risk. The apparatus may include a nasal cannula or face mask and an anesthesia machine having an air flowmeter. The cannula may be in fluid connection with one or more gas outlets on the anesthesia machine. The cannula may provide a user-adjustable reduced Ocontent gas flow to the patient. By providing an Ogas mixture having a lower concentration of O, the present invention significantly mitigates the risk of surgical fires. The apparatus may also include an anesthesia machine having an electronic flowmeter, either alone or in conjunction with the cannula, for maintaining oxygen saturation at a selected level. The apparatus may also include an anesthesia machine having an additional operating mode for use with an open delivery system.

2009013, May 21, 2009

Nov 14, 2008

12/271380

W. Anthony Lee - Gainesville FL, US
Tomas D. Martin - Gainesville FL, US
Nikolaus Gravenstein - Gainesville FL, US

A61B 6/00, A61M 25/10

600435, 604 9601, 6041031, 60410307

Embodiments of the present invention relate to inflatable balloon catheters and methods for deploying an inflatable balloon catheter. For example, one embodiment is directed to a catheter assembly that includes a catheter comprising proximal and distal ends and at least one longitudinal conduit extending between the proximal and distal ends. The catheter assembly also includes an inflatable balloon comprising proximal and distal ends and configured to be at least partially positioned within the longitudinal conduit when the balloon is uninflated. The inflatable balloon is further configured to be inflated when deployed from the conduit such that a diameter of the proximal end of the inflatable balloon remains substantially constant and a diameter of the distal end of the inflatable balloon is variable and capable of at least partially occluding a lumen.

8605133, Dec 10, 2013

Jun 27, 2008

12/530368

Samsun Lampotang - Gainesville FL, US
David Erik Lizdas - Gainesville FL, US
John Joseph Tumino - New Port Richey FL, US
Nikolaus Gravenstein - Gainesville FL, US

University of Florida Research Foundation, Inc. - Gainesville FL

H04N 7/00, G09B 9/00

348 36, 703 6, 463 4, 463 5

The subject invention provides a panoramic, interactive, seamless, intuitive, high-resolution and yet extensive simulation tool capable of simulating dynamic events that alter the panoramic view in response to the user's actions or inaction. The dynamic panorama simulation can generate and display novel scenes that are not limited to static “canned” content that has been previously photographed, rendered, recorded, captured or filmed thus providing great flexibility, contextual authenticity and liveliness and, in some instances, unanticipated and surprising but accurate developments in the simulation.

2008009, Apr 24, 2008

Jul 18, 2005

11/572275

Anatoly E. Martynyuk - Gainesville FL, US
Donn M. Dennis - Gainesville FL, US
Nikolaus Gravenstein - Gainesville FL, US
Alexander V. Glushakov - Gainesville FL, US
Viktor Yarotskyy - Gainesville FL, US
Colin Sumners - Gainesville FL, US
Christoph Seubert - Gainesville FL, US

A61K 31/197, A61K 31/451, A61K 31/496, A61K 31/519, A61K 31/5415, A61K 31/551, A61P 25/00, A61P 25/18

514220, 5142275, 5142278, 51425213, 51425941, 514327, 514567

The subject invention pertains to methods of treating mental illnesses or conditions characterized by a decreased function of NMDA receptors and/or excessively enhanced glutamate release and activity of non-NMDA receptors (AMPA and/or kainate). Specifically disclosed are methods utilizing BrPhe, or isomers of analogs thereof, for treating or preventing mental illness or conditions such as schizophrenia.

4928687, May 29, 1990

Oct 11, 1988

7/255400

Samsun Lampotang - Gainesville FL
Dietrich Gravenstein - Gainesville FL
Joachim S. Gravenstein - Gainesville FL
Nikolaus Gravenstein - Gainesville FL
Michael J. Banner - Gainesville FL

The University of Florida - Gainesville FL

A61M 1600

12820714

A diagnostic monitor checks the carbon dioxide (CO. sub. 2) content of a gas exiting a patient during endotracheal or esophageal intubation. A plurality of composition portions substantially change color in response to exposure to the carbon dioxide. The composition portions change color in response to different times of exposure to carbon dioxide. A magnifying or condensing lens may be positioned on the monitor to enhance viewing of the color change. The monitor may advantageously be made as part of an intubation system through which the gases from a patient exit the patient. The differences in time of exposure needed to cause the color change may be accomplished by using semipermeable membranes having differing thicknesses, CO. sub. 2 permeabilities, and/or surface areas with each membrane corresponding to a particular one of the composition portions.

5180896, Jan 19, 1993

Oct 11, 1990

7/595472

Gordon L. Gibby - Gainesville FL
Samsun Lampotang - Gainesville FL
Daraius Hathiram - Houston TX
Nikolaus Gravenstein - Gainesville FL

University of Florida - Gainseville FL

H05B 664

219 1055A

The heating of blood or other medical fluids supplied to a patient is provided by a system and method of feedback control. The temperature of the blood is sensed by receiving infrared energy from the medical fluid as it flows within a sterile and disposable tube from a fluid source to the patient. Feedback control stabilizes the temperature at a desired value. A second sensor may optionally be used to determine if the fluid is too hot within the microwave device itself. The disposable tube has at least one window or thin membrane portion which allows infrared radiation to pass therethrough in order to be sensed by the sensor. One arrangement of the present invention uses a microprocessor with adaptive control to provide precise and accurate control of the temperature of the medical fluid.

8544115, Oct 1, 2013

Aug 29, 2003

10/652133

Nikolaus Gravenstein - Gainesville FL, US
Dasia Esener - Gainesville FL, US
Samsun Lampotang - Gainesville FL, US
Michael D. Gilmore - Newberry FL, US

University of Florida Research Foundation, Inc. - Gainesville FL

A62B 17/00

2 81

The subject invention provides materials and methods for convective and/or conductive and/or evaporative cooling of individuals, such as athletes and contestants, for safety, comfort, and enhanced performance. The materials and methods of the subject invention can, advantageously, be used to modify body core temperature or rate of change of temperature. Other uses include heating players or player parts (e. g. , a kicker's leg, a pitcher's arm) in cold weather conditions.

2007022, Sep 27, 2007

Apr 18, 2005

11/547459

Nikolaus Gravenstein - Gainesville FL, US
Tammy Euliano - Gainesville FL, US

University of Florida ResearouchFoundation, Inc. - Gainesville FL

A61B 5/042

600376000

A fetal monitoring device directed to a maternal bladder insert having at least one sensor on the distal end to detect fetal vital signs and uterine activity, and methods for detecting fetal vital signs and uterine activity using the device. The bladder insert is preferably a catheter with an integrated electrode for detecting fetal heart rate and uterine electromyography. Furthermore, the device transmits this data to a monitoring system for diagnosis and observation.