Inventors:
George F. Vande Woude - Berryville VA
Nicholas Schulz - Pittsburgh PA
Renping Zhou - Frederick MD
Ira Daar - Frederick MD
Marianne Oskarsson - Gaitherburg MD
Assignee:
The United States of America as represented by the Department of Health
and Human Services - Washington DC
International Classification:
C07D30514
Abstract:
A pharmaceutical composition comprising an effective cancerous cell growth inhibiting amount of paclitaxel, or a paclitaxel derivative, and an effective cancerous cell growth inhibiting amount of an active agent which inhibits cancerous cell growth by exerting an effect on mammalian cell cycle during G. sub. 1 or S-phase of the cell division cycle to inhibit said cancerous cell growth and methods of using same.