Inventors:
Stephen Dewhurst - Rochester NY, US
William J. Bowers - Webster NY, US
Howard J. Federoff - Bethesda MD, US
John G. Frelinger - Pittsford NY, US
Michael C. Keefer - Rochester NY, US
Assignee:
UNIVERSITY OF ROCHESTER - Rochester NY
International Classification:
A61K 39/21, C12N 15/63, C12P 19/34, A61K 39/00, A61P 35/00, A61P 31/18, A61P 25/28, C12Q 1/70
US Classification:
4242081, 4353201, 435 911, 4242771, 4241841, 435 5
Abstract:
Provided herein are HSV amplicon particles and methods of making and using HSV amplicon particles. The particles are generated using primary HSV isolates or packaging vectors derived from primary HSV isolates.