Inventors:
Andrew Lasslo - Memphis TN
Ronald P. Quintana - Germantown TN
Marion Dugdale - Memphis TN
Assignee:
Research Corporation - New York NY
International Classification:
A61K 31445, A61K 3144
Abstract:
A pharmaceutical composition in unit dosage form suitable for administration to an animal in need thereof comprising a pharmaceutically acceptable carrier and an amount sufficient to inhibit blood platelet aggregation of a compound selected from the group consisting of:
[A] A compound having the structural formula: ##STR1## wherein R. sub. 1 is ##STR2## R. sub. 2 is H or ##STR3## and Alk is lower alkyl;
[B] A compound having the structural formula: ##STR4## wherein when R. sub. 3 is ##STR5## n is 8, and when R. sub. 3 is ##STR6## n is 4 or 8, and Alk is lower alkyl;
[C] A compound having the structural formula: ##STR7## wherein when R. sub. 4 is ##STR8## n is 8, and
when R. sub. 4 is ##STR9## n is 0, 1, 4 or 8, and Alk is lower alkyl;
[D] A compound having the structural formula: ##STR10## wherein Alk is lower alkyl; and
[E] Addition salts thereof with pharmaceutically acceptable acids.