Inventors:
Ivan King - North Haven CT, US
Mario Sznol - Woodbridge CT, US
Michael Belcourt - Wallingford CT, US
Assignee:
Vion Pharmaceuticals, Inc. - New Haven CT
International Classification:
A61K 31/175, A61K 31/52, A61K 31/505
US Classification:
514 43, 514 45, 514 46, 514 50, 514 86, 514274, 564 35
Abstract:
This invention provides a method for treating tumor in a subject comprising administering to the subject an effective amount of: (1) VNP40101M, or its equivalent; and (2) a nucleoside, or a nucleoside analog. This invention also provides a method for inhibiting tumor cell growth comprising contacting the tumor cell with effective amounts of: (1) VNP40101M, or its equivalent; and (2) a nucleoside, or a nucleoside analog. The present invention relates to the treatment of cancer, comprising administering to a subject in need thereof an effective amount of VNP40101M in combination with a nucleoside.