Inventors:
Laura S. Schmidt - Mt. Airy MD, US
Michelle Warren - New Market MD, US
Jorge R. Toro - Washington DC, US
Berton Zbar - Garrett Park MD, US
Michael L. Nickerson - Shepherdston WV, US
W. Marston Linehan - North Bethesda MD, US
Maria L. Turner - Washington DC, US
International Classification:
A61K 38/16, C40B 40/06, A61P 17/00, C12Q 1/68, C07K 14/435, C07H 21/04, G01N 33/53
US Classification:
514 186, 536 2431, 536 235, 506 16, 536 245, 436501, 435 611, 530350, 514 212
Abstract:
The present disclosure relates to Birt-Hogg-Dubé syndrome, nucleic acids encoding the BHD gene, and methods of using the nucleic acids and proteins encoded thereby. In particular, the present disclosure relates to methods of diagnosing BHD disease and related conditions, such as spontaneous pneumothorax and kidney cancer, and methods of treating BHD skin lesions.