DR. DOUGLAS RONALD LOWY, M.D.
Dermatology in Bethesda, MD

License number
Maryland 118955-1
Category
Osteopathic Medicine
Type
Dermatology
Address
Address
31 Center Drive Bldg. 31, Bethesda, MD 20852
Phone
(301) 827-5699
(301) 435-2396 (Fax)

Personal information

See more information about DOUGLAS RONALD LOWY at radaris.com
Name
Address
Phone
Douglas Lowy, age 82
8519 Rosewood Dr, Bethesda, MD 20814
Douglas R Lowy, age 82
4709 Chelsea Ln, Bethesda, MD 20814
(301) 652-6373

Professional information

See more information about DOUGLAS RONALD LOWY at trustoria.com
Douglas Lowy Photo 1
Chimeric Papillomavirus-Like Particles

Chimeric Papillomavirus-Like Particles

US Patent:
7691386, Apr 6, 2010
Filed:
Dec 9, 2008
Appl. No.:
12/331368
Inventors:
Douglas R. Lowy - Bethesda MD, US
John T. Schiller - Silver Spring MD, US
Heather Greenstone - Silver Spring MD, US
Assignee:
The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services - Rockville MD
International Classification:
A61K 39/00
US Classification:
4241921
Abstract:
The present invention provides a papillomavirus-like particle, characterized as having conformational epitopes, comprising a papillomavirus L1 product and a papillomavirus L2 fusion product; and related synthetic DNA molecules, host cells, methods and vaccines.


Douglas Lowy Photo 2
Virus-Like Particles For The Induction Of Autoantibodies

Virus-Like Particles For The Induction Of Autoantibodies

US Patent:
7875450, Jan 25, 2011
Filed:
Mar 18, 2008
Appl. No.:
12/050892
Inventors:
John T. Schiller - Silver Spring MD, US
Bryce Chackerian - Chevy Chase MD, US
Douglas R. Lowy - Bethesda MD, US
Assignee:
The United States of America as represented by the Department of Health and Human Services - Washington DC
International Classification:
A61K 31/00, C12P 21/01
US Classification:
4353201, 424 931, 435 691
Abstract:
The invention described herein relates to compositions and methods for stimulating immune responses in vivo against a tolerogen. Novel biotechnological tools, pharmaceuticals, therapeutics and prophylactics, which concern chimeric or conjugated virus-like particles, and methods of use of the foregoing are provided for the study of B cell tolerance and the treatment or prevention of human diseases, which involve the onset of B cell tolerance, such as chronic viral infection, chronic inflammatory disease, and neoplasia.


Douglas Lowy Photo 3
Ichimeric Papillomavirus-Like Particles

Ichimeric Papillomavirus-Like Particles

US Patent:
5855891, Jan 5, 1999
Filed:
Jan 9, 1997
Appl. No.:
8/781084
Inventors:
Douglas R. Lowy - Bethesda MD
John T. Schiller - Silver Spring MD
Heather Greenstone - Silver Spring MD
Assignee:
The United States of America as represented by the Department of Health
and Human Services - Washington DC
International Classification:
A61K 3900, A61K 3912, C12P 2106, C12N 700
US Classification:
4241921
Abstract:
The present invention provides a papillomavirus-like particle having conformational epitopes comprising a papillomavirus L1 fusion product and, optionally, a papillomavirus L2 product; and related DNA molecules, host cells, and methods.


Douglas Lowy Photo 4
Infectious Papillomavirus Pseudoviral Particles

Infectious Papillomavirus Pseudoviral Particles

US Patent:
2003020, Nov 6, 2003
Filed:
May 27, 2003
Appl. No.:
10/446060
Inventors:
Douglas Lowy - Bethesda MD, US
John Schiller - Silver Spring MD, US
Richard Roden - Washington DC, US
International Classification:
A61K048/00, C12N007/00, C12N015/86
US Classification:
435/325000, 435/456000, 435/235100, 424/093200
Abstract:
The invention provides an infectious papillomavirus pseudoviral particle useful in gene transfer comprising: (a) a papillomavirus vector DNA which comprises an E2 binding site and an expression cassette comprising a gene and a sequence controlling expression of said gene; and (b) a papillomavirus capsid which comprises L1 and L2 structural proteins, such that said capsid encapsidates said vector DNA, wherein said gene is derived from a first biological species and said L1 structural protein is derived from a second biological species and said first biological species is different from said second biological species.


Douglas Lowy Photo 5
Virus-Like Particles For The Induction Of Autoantibodies

Virus-Like Particles For The Induction Of Autoantibodies

US Patent:
7479280, Jan 20, 2009
Filed:
May 1, 2006
Appl. No.:
11/415611
Inventors:
John T. Schiller - Silver Spring MD, US
Bryce Chackerian - Chevy Chase MD, US
Douglas R. Lowy - Bethesda MD, US
Assignee:
The United States of America as represented by the Department of Health and Human Services - Washington DC
International Classification:
A61A 39/00, A61A 39/12, A61A 47/48, A61P 29/00, A61P 31/12, A61P 31/18
US Classification:
4241991, 4353021, 435 691, 435 9133
Abstract:
The invention described herein relates to compositions and methods for stimulating immune responses in vivo against a tolerogen. Novel biotechnological tools, pharmaceuticals, therapeutics and prophylactics, which concern chimeric or conjugated virus-like particles, and methods of use of the foregoing are provided for the study of B cell tolerance and the treatment or prevention of human diseases, which involve the onset of B cell tolerance, such as chronic viral infection, chronic inflammatory disease, and neoplasia.


Douglas Lowy Photo 6
Chimeric Papillomavirus-Like Particles

Chimeric Papillomavirus-Like Particles

US Patent:
7462356, Dec 9, 2008
Filed:
May 25, 2007
Appl. No.:
11/807004
Inventors:
Douglas R. Lowy - Bethesda MD, US
John T. Schiller - Silver Spring MD, US
Heather Greenstone - Silver Spring MD, US
Assignee:
The United States of America, as represented by the Department of Health and Human Services - Washington DC
International Classification:
A61K 39/12
US Classification:
4242041, 4241921, 435 6
Abstract:
The present invention provides a papillomavirus-like particle, characterized as having conformational epitopes, comprising a papillomavirus L1 product and a papillomavirus L2 fusion product; and related synthetic DNA molecules, host cells, methods and vaccines.


Douglas Lowy Photo 7
Virus-Like Particles For The Induction Of Autoantibodies

Virus-Like Particles For The Induction Of Autoantibodies

US Patent:
2003007, Apr 17, 2003
Filed:
Sep 24, 2002
Appl. No.:
10/253443
Inventors:
John Schiller - Silver Spring MD, US
Bryce Chackerian - Chevy Chase MD, US
Douglas Lowy - Bethesda MD, US
International Classification:
A61K039/395, A61K039/12
US Classification:
424/140100, 424/204100
Abstract:
The invention described herein relates to compositions and methods for stimulating immune responses in vivo against a tolerogen. Novel biotechnological tools, pharmaceuticals, therapeutics and prophylactics, which concern chimeric or conjugated virus-like particles, and methods of use of the foregoing are provided for the study of B cell tolerance and the treatment or prevention of human diseases, which involve the onset of B cell tolerance, such as chronic viral infection, chronic inflammatory disease, and neoplasia.


Douglas Lowy Photo 8
Papillomavirus Pseudoviruses For Detection And Therapy Of Tumors

Papillomavirus Pseudoviruses For Detection And Therapy Of Tumors

US Patent:
2013023, Sep 5, 2013
Filed:
Feb 8, 2013
Appl. No.:
13/763365
Inventors:
The USA as represented by the Secretary, Dept. of Health and Human Services; National Institute of Health - , US
Douglas R. Lowy - Bethesda MD, US
John T. Schiller - Kensington MD, US
Assignee:
The USA as represented by the Secretary, Dept. of Health and Human Services; National Institutes of - Bethesda MD
International Classification:
A61K 51/12, A61K 49/00
US Classification:
424 117, 424 91, 424 96, 424 92
Abstract:
Disclosed herein are methods of detecting tumors, monitoring cancer therapy, and selectively inhibiting the proliferation and/or killing of cancer cells utilizing a papilloma pseudovirus or a papilloma virus-like particle (VLP)


Douglas Lowy Photo 9
Chimeric Papillomavirus-Like Particles

Chimeric Papillomavirus-Like Particles

US Patent:
2004013, Jul 8, 2004
Filed:
Dec 19, 2003
Appl. No.:
10/741613
Inventors:
Douglas Lowy - Bethesda MD, US
John Schiller - Silver Spring MD, US
Heather Greenstone - Silver Spring MD, US
International Classification:
C12N015/86, C12N007/00
US Classification:
435/235100, 435/456000
Abstract:
The present invention provides a papillomavirus-like particle, characterized as having conformational epitopes, comprising a papillomavirus L1 product and a papillomavirus L2 fusion product; and related synthetic DNA molecules, host cells, methods and vaccines.


Douglas Lowy Photo 10
Chimeric Papillomavirus-Like Particles

Chimeric Papillomavirus-Like Particles

US Patent:
2003017, Sep 11, 2003
Filed:
Apr 1, 2003
Appl. No.:
10/405264
Inventors:
Douglas Lowy - Bethesda MD, US
John Schiller - Silver Spring MD, US
Heather Greenstone - Silver Spring MD, US
International Classification:
C07H021/04, C12P019/34, A61K039/12, C07K002/00, C07K004/00, C07K005/00, C07K007/00, C07K014/00, C07K016/00, C07K017/00, A61K038/00
US Classification:
424/204100, 424/186100, 435/091100, 536/023720, 530/300000
Abstract:
The present invention provides a papillomavirus-like particle, characterized as having conformational epitopes, comprising a papillomavirus L1 product and a papillomavirus L2 fusion product; and related synthetic DNA molecules, host cells, methods and vaccines.