DR. DOUGLAS RONALD LOWY, M.D.
Dermatology in Bethesda, MD
License number
Maryland 118955-1
Category
Osteopathic Medicine
Type
Dermatology
Address
Address
31 Center Drive Bldg. 31, Bethesda, MD 20852
Phone
(301) 827-5699
(301) 435-2396 (Fax)
(301) 435-2396 (Fax)
Personal information
See more information about DOUGLAS RONALD LOWY at radaris.comName
Address
Phone
8519 Rosewood Dr, Bethesda, MD 20814
4709 Chelsea Ln, Bethesda, MD 20814
Professional information
Chimeric Papillomavirus-Like Particles
US Patent:
7691386, Apr 6, 2010
Filed:
Dec 9, 2008
Appl. No.:
12/331368
Inventors:
Douglas R. Lowy - Bethesda MD, US
John T. Schiller - Silver Spring MD, US
Heather Greenstone - Silver Spring MD, US
John T. Schiller - Silver Spring MD, US
Heather Greenstone - Silver Spring MD, US
Assignee:
The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services - Rockville MD
International Classification:
A61K 39/00
US Classification:
4241921
Abstract:
The present invention provides a papillomavirus-like particle, characterized as having conformational epitopes, comprising a papillomavirus L1 product and a papillomavirus L2 fusion product; and related synthetic DNA molecules, host cells, methods and vaccines.
Virus-Like Particles For The Induction Of Autoantibodies
US Patent:
7875450, Jan 25, 2011
Filed:
Mar 18, 2008
Appl. No.:
12/050892
Inventors:
John T. Schiller - Silver Spring MD, US
Bryce Chackerian - Chevy Chase MD, US
Douglas R. Lowy - Bethesda MD, US
Bryce Chackerian - Chevy Chase MD, US
Douglas R. Lowy - Bethesda MD, US
Assignee:
The United States of America as represented by the Department of Health and Human Services - Washington DC
International Classification:
A61K 31/00, C12P 21/01
US Classification:
4353201, 424 931, 435 691
Abstract:
The invention described herein relates to compositions and methods for stimulating immune responses in vivo against a tolerogen. Novel biotechnological tools, pharmaceuticals, therapeutics and prophylactics, which concern chimeric or conjugated virus-like particles, and methods of use of the foregoing are provided for the study of B cell tolerance and the treatment or prevention of human diseases, which involve the onset of B cell tolerance, such as chronic viral infection, chronic inflammatory disease, and neoplasia.
Ichimeric Papillomavirus-Like Particles
US Patent:
5855891, Jan 5, 1999
Filed:
Jan 9, 1997
Appl. No.:
8/781084
Inventors:
Douglas R. Lowy - Bethesda MD
John T. Schiller - Silver Spring MD
Heather Greenstone - Silver Spring MD
John T. Schiller - Silver Spring MD
Heather Greenstone - Silver Spring MD
Assignee:
The United States of America as represented by the Department of Health
and Human Services - Washington DC
and Human Services - Washington DC
International Classification:
A61K 3900, A61K 3912, C12P 2106, C12N 700
US Classification:
4241921
Abstract:
The present invention provides a papillomavirus-like particle having conformational epitopes comprising a papillomavirus L1 fusion product and, optionally, a papillomavirus L2 product; and related DNA molecules, host cells, and methods.
Infectious Papillomavirus Pseudoviral Particles
US Patent:
2003020, Nov 6, 2003
Filed:
May 27, 2003
Appl. No.:
10/446060
Inventors:
Douglas Lowy - Bethesda MD, US
John Schiller - Silver Spring MD, US
Richard Roden - Washington DC, US
John Schiller - Silver Spring MD, US
Richard Roden - Washington DC, US
International Classification:
A61K048/00, C12N007/00, C12N015/86
US Classification:
435/325000, 435/456000, 435/235100, 424/093200
Abstract:
The invention provides an infectious papillomavirus pseudoviral particle useful in gene transfer comprising: (a) a papillomavirus vector DNA which comprises an E2 binding site and an expression cassette comprising a gene and a sequence controlling expression of said gene; and (b) a papillomavirus capsid which comprises L1 and L2 structural proteins, such that said capsid encapsidates said vector DNA, wherein said gene is derived from a first biological species and said L1 structural protein is derived from a second biological species and said first biological species is different from said second biological species.
Virus-Like Particles For The Induction Of Autoantibodies
US Patent:
7479280, Jan 20, 2009
Filed:
May 1, 2006
Appl. No.:
11/415611
Inventors:
John T. Schiller - Silver Spring MD, US
Bryce Chackerian - Chevy Chase MD, US
Douglas R. Lowy - Bethesda MD, US
Bryce Chackerian - Chevy Chase MD, US
Douglas R. Lowy - Bethesda MD, US
Assignee:
The United States of America as represented by the Department of Health and Human Services - Washington DC
International Classification:
A61A 39/00, A61A 39/12, A61A 47/48, A61P 29/00, A61P 31/12, A61P 31/18
US Classification:
4241991, 4353021, 435 691, 435 9133
Abstract:
The invention described herein relates to compositions and methods for stimulating immune responses in vivo against a tolerogen. Novel biotechnological tools, pharmaceuticals, therapeutics and prophylactics, which concern chimeric or conjugated virus-like particles, and methods of use of the foregoing are provided for the study of B cell tolerance and the treatment or prevention of human diseases, which involve the onset of B cell tolerance, such as chronic viral infection, chronic inflammatory disease, and neoplasia.
Chimeric Papillomavirus-Like Particles
US Patent:
7462356, Dec 9, 2008
Filed:
May 25, 2007
Appl. No.:
11/807004
Inventors:
Douglas R. Lowy - Bethesda MD, US
John T. Schiller - Silver Spring MD, US
Heather Greenstone - Silver Spring MD, US
John T. Schiller - Silver Spring MD, US
Heather Greenstone - Silver Spring MD, US
Assignee:
The United States of America, as represented by the Department of Health and Human Services - Washington DC
International Classification:
A61K 39/12
US Classification:
4242041, 4241921, 435 6
Abstract:
The present invention provides a papillomavirus-like particle, characterized as having conformational epitopes, comprising a papillomavirus L1 product and a papillomavirus L2 fusion product; and related synthetic DNA molecules, host cells, methods and vaccines.
Virus-Like Particles For The Induction Of Autoantibodies
US Patent:
2003007, Apr 17, 2003
Filed:
Sep 24, 2002
Appl. No.:
10/253443
Inventors:
John Schiller - Silver Spring MD, US
Bryce Chackerian - Chevy Chase MD, US
Douglas Lowy - Bethesda MD, US
Bryce Chackerian - Chevy Chase MD, US
Douglas Lowy - Bethesda MD, US
International Classification:
A61K039/395, A61K039/12
US Classification:
424/140100, 424/204100
Abstract:
The invention described herein relates to compositions and methods for stimulating immune responses in vivo against a tolerogen. Novel biotechnological tools, pharmaceuticals, therapeutics and prophylactics, which concern chimeric or conjugated virus-like particles, and methods of use of the foregoing are provided for the study of B cell tolerance and the treatment or prevention of human diseases, which involve the onset of B cell tolerance, such as chronic viral infection, chronic inflammatory disease, and neoplasia.
Papillomavirus Pseudoviruses For Detection And Therapy Of Tumors
US Patent:
2013023, Sep 5, 2013
Filed:
Feb 8, 2013
Appl. No.:
13/763365
Inventors:
The USA as represented by the Secretary, Dept. of Health and Human Services; National Institute of Health - , US
Douglas R. Lowy - Bethesda MD, US
John T. Schiller - Kensington MD, US
Douglas R. Lowy - Bethesda MD, US
John T. Schiller - Kensington MD, US
Assignee:
The USA as represented by the Secretary, Dept. of Health and Human Services; National Institutes of - Bethesda MD
International Classification:
A61K 51/12, A61K 49/00
US Classification:
424 117, 424 91, 424 96, 424 92
Abstract:
Disclosed herein are methods of detecting tumors, monitoring cancer therapy, and selectively inhibiting the proliferation and/or killing of cancer cells utilizing a papilloma pseudovirus or a papilloma virus-like particle (VLP)
Chimeric Papillomavirus-Like Particles
US Patent:
2004013, Jul 8, 2004
Filed:
Dec 19, 2003
Appl. No.:
10/741613
Inventors:
Douglas Lowy - Bethesda MD, US
John Schiller - Silver Spring MD, US
Heather Greenstone - Silver Spring MD, US
John Schiller - Silver Spring MD, US
Heather Greenstone - Silver Spring MD, US
International Classification:
C12N015/86, C12N007/00
US Classification:
435/235100, 435/456000
Abstract:
The present invention provides a papillomavirus-like particle, characterized as having conformational epitopes, comprising a papillomavirus L1 product and a papillomavirus L2 fusion product; and related synthetic DNA molecules, host cells, methods and vaccines.
Chimeric Papillomavirus-Like Particles
US Patent:
2003017, Sep 11, 2003
Filed:
Apr 1, 2003
Appl. No.:
10/405264
Inventors:
Douglas Lowy - Bethesda MD, US
John Schiller - Silver Spring MD, US
Heather Greenstone - Silver Spring MD, US
John Schiller - Silver Spring MD, US
Heather Greenstone - Silver Spring MD, US
International Classification:
C07H021/04, C12P019/34, A61K039/12, C07K002/00, C07K004/00, C07K005/00, C07K007/00, C07K014/00, C07K016/00, C07K017/00, A61K038/00
US Classification:
424/204100, 424/186100, 435/091100, 536/023720, 530/300000
Abstract:
The present invention provides a papillomavirus-like particle, characterized as having conformational epitopes, comprising a papillomavirus L1 product and a papillomavirus L2 fusion product; and related synthetic DNA molecules, host cells, methods and vaccines.
Dermatology licenses in Maryland
MARGARET REBA STEVENS ONEILL MD, LLC, Dermatology, 5454 Wisconsin Ave SUITE 1400, Bethesda, MD 20815