Inventors:
William G. Kerr - Syracuse NY, US
Caroline Desponts - La Jolla CA, US
Lia Elena Perez - Tampa FL, US
Assignee:
UNIVERSITY OF SOUTH FLORIDA - Tampa FL
International Classification:
A61K 35/12, A61K 31/7052, C12N 5/00, A61P 7/00
US Classification:
424 937, 514 44 A, 435375
Abstract:
A method of increasing megakaryocytes and platelet numbers in a patient comprising the step of inhibiting SHIP expression, including SHIP's enzymatic activity and signaling functions, whereby normal blood clotting is induced.