DR. LAURENCE M KATZ, MD
Osteopathic Medicine at Manning Dr, Chapel Hill, NC
License number
North Carolina 9601126
Category
Osteopathic Medicine
Type
Emergency Medicine
Address
Address
101 Manning Dr, Chapel Hill, NC 27599
Phone
(919) 966-4996
(919) 843-5515 (Fax)
(919) 843-5515 (Fax)
Professional information
Laurence M Katz, Chapel Hill NC
Specialties:
Emergency Medicine Physician
Address:
101 Manning Dr, Chapel Hill, NC 27514
Board certifications:
American Board of Emergency Medicine Certification in Emergency Medicine, American Board of Internal Medicine Certification in Internal Medicine
Dr. Laurence M Katz, Chapel Hill NC - MD (Doctor of Medicine)
Specialties:
Internal Medicine, Emergency Medicine
Address:
University North Carolina EMR
101 Manning Dr, Chapel Hill 27514
(919) 966-4131 (Phone)
101 Manning Dr, Chapel Hill 27514
(919) 966-4131 (Phone)
Certifications:
Emergency Medicine, 2004, Internal Medicine, 2000
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
University North Carolina EMR
101 Manning Dr, Chapel Hill 27514
University of North Carolina Hospital
101 Manning Dr, Chapel Hill 27514
101 Manning Dr, Chapel Hill 27514
University of North Carolina Hospital
101 Manning Dr, Chapel Hill 27514
Education:
Medical School
University of Medicine And Dentistry of New Jersey / Robert Wood Johnson Medical School
Graduated: 1987
Deaconess Hospital
University Of Pittsburgh Med Center
University of Medicine And Dentistry of New Jersey / Robert Wood Johnson Medical School
Graduated: 1987
Deaconess Hospital
University Of Pittsburgh Med Center
Methods And Compositions For The Induction Of Hypothermia
US Patent:
2012028, Nov 8, 2012
Filed:
Jun 9, 2010
Appl. No.:
13/377257
Inventors:
Laurence M. Katz - Chapel Hill NC, US
International Classification:
A61K 38/11, A61P 25/00, A61P 9/10, A61P 9/00, A61K 38/28, A61K 35/12
US Classification:
424 937, 514 109, 514 65
Abstract:
Provided herein are methods for the induction of hypothermia and the treatment of clinical insults in a subject through the administration of a regulated hypothermic multidrug combination. The compositions or multidrug combinations of the invention comprise a regulated hypothermic compound or a dopamine receptor agonist; a vasoactive compound; and an antiarrhythmic compound or a serotonin 5-HT3 receptor antagonist. Additional agents can be included in the composition including at least one of an antioxidant, a vitamin, N-acetylcysteine, and an antihyperglycemic compound. The invention further recognizes that a two phase delivery of multidrug combinations, a rapid infusion of the composition to induce hypothermia followed by a period of slow infusion to maintain the hypothermic state for a sustained period of time. Using the two phase delivery method of the invention, the composition may comprise ethanol and, optionally, at least one of a vasoactive compound, an antiarrhythmic compound, a serotonin 5-HT3 receptor antagonist, an antioxidant, a vitamin, N-acetylcysteine, and an antihyperglycemic compound. This two phase delivery method can be used to deliver any of the compositions of the invention and provides significant benefits to a patient.
Methods Of Treating Cerebral Ischemia
US Patent:
7319090, Jan 15, 2008
Filed:
Nov 27, 2002
Appl. No.:
10/306672
Inventors:
Laurence M. Katz - Chapel Hill NC, US
Assignee:
University of North Carolina at Chapel Hill - Chapel Hill NC
International Classification:
A61K 31/17, A61K 31/404
US Classification:
514 12, 514 14, 514415, 514419
Abstract:
The present invention provides methods of treating cerebral ischemia in mammals comprising inducing hypothermia in a mammal before, during, or following cerebral ischemia in the mammal. The hypothermia is induced by administering to the mammal an effective dose of a neurotensin analog that is capable of crossing the blood-brain barrier and that comprises neo-tryptophan.