Inventors:
Joseph Desimone - Chapel Hill NC, US
Mary Napier - Carrboro NC, US
Jonathan Pillai - Chapel Hill NC, US
James Byrne - Chapel Hill NC, US
Lukas Miller Roush - Chapel Hill NC, US
Jen Jen Yeh - Chapel Hill NC, US
Matt Parrott - Carrboro NC, US
Assignee:
LIQUIDIA TECHNOLOGIES, INC. - Durham NC
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL - Chapel Hill NC
International Classification:
A61M 5/00, A61B 6/00
Abstract:
A delivery system for local drug delivery to a target site of internal body tissue is provided. The delivery system comprises a source electrode adapted to be positioned proximate to a target site of internal body tissue. A counter electrode is in electrical communication with the source electrode, and is configured to cooperate with the source electrode to form a localized electric field proximate to the target site. A reservoir is configured to be disposed such that the reservoir is capable of interacting with the localized electric field. The reservoir is configured to carry a cargo capable of being delivered to the target site when exposed to the localized electric field. Associated methods are also provided.