Inventors:
The General Hospital Corporation - , US
Laura M. Calvi - Rochester NY, US
Gregor Adams - Boston MA, US
Henry M. Kronenberg - Belmont MA, US
International Classification:
A61K 38/29, G01N 33/74, C12N 5/0797, C12Q 1/68, C12N 5/0775, C12N 5/071
US Classification:
514 118, 435377, 435 613, 435 792, 435 721
Abstract:
The invention relates to methods for manipulating hematopoietic stem or progenitor cells, mesenchymal stem cells, epithelial stem cells, neural stem cells and related products through activation of the PTH/PTHrP receptor in neighboring cells.