LAURA M BRIGGS
Real Estate Commission in Reno, NV
License number
Nevada 173166
Category
Real Estate Appraisers
Type
Salesperson
Address
Address
Reno, NV 89521
Professional information
Biology Lab Coordinator At Truckee Meadows Community College
Position:
Biology Lab Coordinator at Truckee Meadows Community College, Vice President Research and Discovery at Sierra Sciences, LLC
Location:
Reno, Nevada Area
Industry:
Higher Education
Work:
Truckee Meadows Community College
since Feb 2006
-
Biology Lab Coordinator
Sierra Sciences, LLC
since Jun 2001
-
Vice President Research and Discovery
Assays For Tert Promoter Modulatory Agents Using A Telomerase Structural Rna Component
US Patent:
7226744, Jun 5, 2007
Filed:
Mar 21, 2005
Appl. No.:
11/085872
Inventors:
William H. Andrews - Reno NV, US
Laura Briggs - Reno NV, US
Lancer K. Brown - Sparks NV, US
Christopher A. Foster - Reno NV, US
Mieczyslaw A. Piatyszek - Morgan Hill CA, US
Laura Briggs - Reno NV, US
Lancer K. Brown - Sparks NV, US
Christopher A. Foster - Reno NV, US
Mieczyslaw A. Piatyszek - Morgan Hill CA, US
Assignee:
Sierra Sciences, Inc. - Reno NV
International Classification:
C12Q 1/68
US Classification:
435 6, 435455
Abstract:
Methods and compositions for assaying an agent for TERT promoter modulatory activity are provided. In the subject methods, an agent is contacted with a cell comprising a mutant telomerase structural RNA component (TR) that results in a detectable phenotype in the presence of telomerase reverse transcriptase (TERT). Also provided are compositions, systems and kits thereof, as well as devices, that find use in practicing the subject methods. The subject invention finds use in assaying agents for TERT promoter modulatory activity, such as in a high throughput format.
Methods And Compositions For Use In Selectively Producing A Protein In Telomerase Expressing Cells
US Patent:
2003011, Jun 19, 2003
Filed:
Aug 13, 2002
Appl. No.:
10/219450
Inventors:
William Andrews - Reno NV, US
Daniel Fylstra - Incline Village NV, US
Christopher Foster - Carmichael CA, US
Stephanie Fraser - Sparks NV, US
Hamid Mohammadpour - Reno NV, US
Laura Briggs - Reno NV, US
Daniel Fylstra - Incline Village NV, US
Christopher Foster - Carmichael CA, US
Stephanie Fraser - Sparks NV, US
Hamid Mohammadpour - Reno NV, US
Laura Briggs - Reno NV, US
International Classification:
C12Q001/68, C12P021/02, C12N005/06
US Classification:
435/006000, 435/069100, 435/320100, 435/325000
Abstract:
Methods and compositions for use in selectively expressing a protein in a telomerase expressing cell are provided. In the subject methods, an expression cassette comprising a Site C repressor site and a coding sequence for the protein is introduced into the target telomerase expressing cell, e.g., by administering the expression cassette to a host that includes the target cell. The protein may be a therapeutic or diagnostic protein. The subject methods find use in a variety of different applications, and are particularly suited for use in diagnostic and therapeutic applications, e.g., of cellular proliferative disease conditions.
Methods And Compositions For Modulating Telomerase Reverse Transcriptase (Tert) Expression
US Patent:
2008026, Oct 30, 2008
Filed:
Jan 18, 2008
Appl. No.:
12/009638
Inventors:
William H. Andrews - Reno NV, US
Laura Briggs - Reno NV, US
Christopher A. Foster - Carmichael CA, US
Hamid Mohammadpour - Reno NV, US
Stephanie Fraser - Sparks NV, US
Lancer Brown - Sparks NV, US
Frederick M. Hahn - San Rafael CA, US
Laura Briggs - Reno NV, US
Christopher A. Foster - Carmichael CA, US
Hamid Mohammadpour - Reno NV, US
Stephanie Fraser - Sparks NV, US
Lancer Brown - Sparks NV, US
Frederick M. Hahn - San Rafael CA, US
International Classification:
G01N 33/53, C07K 1/00, C12N 5/06, C12N 9/00
US Classification:
435 72, 530402, 435375, 435183, 435 78
Abstract:
Methods and compositions are provided for modulating, e.g., increasing or decreasing, the expression of telomerase reverse transcriptase (TERT). In the subject methods, the binding interaction of the TERT Site C repressor site with a Site C repressor protein complex made up of one or more proteins is modulated to achieve the desired change in TERT expression. A feature of the subject invention is that the target Site C repressor protein complex includes a MRG15 protein. The subject methods and compositions find use in a variety of different applications, including the immortalization of cells, the production of reagents for use in life science research, therapeutic applications; therapeutic agent screening applications; and the like.
Telomerase Expression Repressor Proteins And Methods Of Using The Same
US Patent:
2005017, Aug 11, 2005
Filed:
Mar 12, 2002
Appl. No.:
10/477646
Inventors:
William Andrews - Reno NV, US
Christopher Foster - Reno NV, US
Stephane Fraser - Sparks NV, US
Hamid Mohammadpour - Reno NV, US
Laura Briggs - Reno NV, US
Christopher Foster - Reno NV, US
Stephane Fraser - Sparks NV, US
Hamid Mohammadpour - Reno NV, US
Laura Briggs - Reno NV, US
International Classification:
A61K038/17
US Classification:
514012000
Abstract:
Telomerase repressor proteins and nucleic acid compositions encoding the same are provided. The subject repressor proteins bind to a repressor site in the TERT minimal promoter, e.g., a Site C site, and thereby inhibit TERT expression. Also provided are methods of modulating, e.g., inhibiting or enhancing, TERT expression. The subject invention finds use in a variety of different applications, including therapeutic and therapeutic agent screening applications.
Telomerase Expression Repressor Proteins And Methods Of Using The Same
US Patent:
7211435, May 1, 2007
Filed:
Jun 21, 2002
Appl. No.:
10/177744
Inventors:
William H. Andrews - Reno NV, US
Christopher A. Foster - Carmichael CA, US
Stephanie Fraser - Sparks NV, US
Hamid Mohammadpour - Reno NV, US
Laura Briggs - Reno NV, US
Christopher A. Foster - Carmichael CA, US
Stephanie Fraser - Sparks NV, US
Hamid Mohammadpour - Reno NV, US
Laura Briggs - Reno NV, US
Assignee:
Sierra Sciences, Inc. - Reno NV
International Classification:
C12N 15/85
US Classification:
435455, 536 231, 536 241, 530350
Abstract:
Telomerase repressor proteins and nucleic acid compositions encoding the same are provided. The subject repressor proteins bind to a repressor site in the TERT minimal promoter, e. g. , a Site C site, and thereby inhibit TERT expression. Also provided are methods of modulating, e. g. , inhibiting or enhancing, TERT expression. The subject invention finds use in a variety of different applications, including therapeutic and therapeutic agent screening applications.
Telomerase Expression Repressor Proteins And Methods Of Using The Same
US Patent:
7795416, Sep 14, 2010
Filed:
Mar 20, 2007
Appl. No.:
11/726388
Inventors:
William H. Andrews - Reno NV, US
Christopher A. Foster - Carmichael CA, US
Stephanie Fraser - Sparks NV, US
Hamid Mohammadpour - Reno NV, US
Laura Briggs - Reno NV, US
Christopher A. Foster - Carmichael CA, US
Stephanie Fraser - Sparks NV, US
Hamid Mohammadpour - Reno NV, US
Laura Briggs - Reno NV, US
Assignee:
Sierra Sciences Inc. - Reno NV
International Classification:
C07H 21/04, C12N 15/85
US Classification:
536 241, 435455
Abstract:
Telomerase repressor proteins and nucleic acid compositions encoding the same are provided. The subject repressor proteins bind to a repressor site in the TERT minimal promoter, e. g. , a Site C site, and thereby inhibit TERT expression. Also provided are methods of modulating, e. g. , inhibiting or enhancing, TERT expression. The subject invention finds use in a variety of different applications, including therapeutic and therapeutic agent screening applications.
Telomerase Expression Repressor Proteins And Methods Of Using The Same
US Patent:
2009023, Sep 24, 2009
Filed:
Jun 4, 2008
Appl. No.:
12/133082
Inventors:
William H. Andrews - Reno NV, US
Christopher A. Foster - Reno NV, US
Stephanie Fraser - Sparks NV, US
Hamid Mohammadpour - Reno NV, US
Laura Briggs - Reno NV, US
Christopher A. Foster - Reno NV, US
Stephanie Fraser - Sparks NV, US
Hamid Mohammadpour - Reno NV, US
Laura Briggs - Reno NV, US
International Classification:
C12Q 1/68, C12N 9/99
US Classification:
435 6, 435184
Abstract:
Telomerase repressor proteins and nucleic acid compositions encoding the same are provided. The subject repressor proteins bind to a repressor site in the TERT minimal promoter, e.g., a Site C site, and thereby inhibit TERT expression. Also provided are methods of modulating, e.g., inhibiting or enhancing, TERT expression. The subject invention finds use in a variety of different applications, including therapeutic and therapeutic agent screening applications.
Methods And Compositions For Modulating Telomerase Reverse Transcriptase (Tert) Expression
US Patent:
7279328, Oct 9, 2007
Filed:
Apr 16, 2004
Appl. No.:
10/826466
Inventors:
William H. Andrews - Reno NV, US
Christopher A. Foster - Carmichael CA, US
Stephanie Fraser - Sparks NV, US
Hamid Mohammadpour - Reno NV, US
Laura Briggs - Reno NV, US
Christopher A. Foster - Carmichael CA, US
Stephanie Fraser - Sparks NV, US
Hamid Mohammadpour - Reno NV, US
Laura Briggs - Reno NV, US
Assignee:
Sierra Sciences, Inc. - Reno NV
International Classification:
C12N 5/00
US Classification:
435325, 435 6
Abstract:
Methods and compositions are provided for modulating, e. g. , increasing or decreasing, the expression of telomerase reverse transcriptase (TERT). In the subject methods, the binding interaction of the GC-Box 5 repressor site with a repressor protein (or protein complex including the same) is modulated to achieve the desired change in TERT expression. The subject methods and compositions find use in a variety of different applications, including the immortalization of cells, the production of reagents for use in life science research, therapeutic applications; therapeutic agent screening applications; and the like.
Compounds That Increase Telomerase Reverse Transcriptase (Tert) Expression And Methods For Using The Same
US Patent:
2009014, Jun 4, 2009
Filed:
Nov 13, 2008
Appl. No.:
12/270552
Inventors:
William H. Andrews - Reno NV, US
Laura A. Briggs - Reno NV, US
Christopher A. Foster - Carmichael CA, US
Lancer K. Brown - Sparks NV, US
Mieczyslaw A. Piatyszek - Morgan Hill CA, US
Federico C.A. Gaeta - Mountain View CA, US
Munirathnam Chaguturu - Lawrence KS, US
Jian Zhang - Fremont CA, US
Tom Kerley - Gardnerville NV, US
Laura A. Briggs - Reno NV, US
Christopher A. Foster - Carmichael CA, US
Lancer K. Brown - Sparks NV, US
Mieczyslaw A. Piatyszek - Morgan Hill CA, US
Federico C.A. Gaeta - Mountain View CA, US
Munirathnam Chaguturu - Lawrence KS, US
Jian Zhang - Fremont CA, US
Tom Kerley - Gardnerville NV, US
International Classification:
A61K 31/422, C12N 5/02, C12Q 1/02
US Classification:
514378, 435375, 435 29
Abstract:
Compounds, and methods of using the same, are provided which increase the expression of telomerase reverse transcriptase (TERT) in a cell. These compounds and methods find use in a variety of applications in which increased expression of telomerase is desired, including immortalization of cell lines and treating conditions in a subject characterized by cellular senescence.