Inventors:
Neil Bander - Chappaqua NY, US
Joseph Osborne - New York NY, US
Stanley J. Goldsmith - Floral Park NY, US
Shankar Vallabhajosula - Larchmont NY, US
Assignee:
Cornell Research Foundation, Inc. - Ithaca NY
International Classification:
A61K 51/10, A61K 49/06, A61K 49/14, G01N 33/53, A61P 35/00
US Classification:
424 149, 424 934, 424 94, 435 71
Abstract:
A method for identifying a patient for cancer therapy can include administering a diagnostic dose of a detectably labeled first binding agent to a patient, the detectably labeled binding agent being capable of binding a molecular target. The method also includes selecting a patient for administration of a therapeutic dose of a second binding agent capable of binding a cellular target, wherein the selected patient exhibits a positive reading for the detectably labeled first binding agent. Furthermore, the method can include administering a therapeutic dose of the second binding agent to the patient.