DR. JOSEPH C WU, MD
Osteopathic Medicine in Palo Alto, CA

License number
California A066551
Category
Osteopathic Medicine
Type
Internal Medicine
License number
California A066551
Category
Osteopathic Medicine
Type
Cardiovascular Disease
Address
Address 2
300 Pasteur Dr Edwards BUILDING R354, Palo Alto, CA 94305
174 Louise Ln, San Mateo, CA 94403
Phone
(650) 736-2246
(650) 736-0234 (Fax)

Professional information

Joseph Chong-Sang Wu Photo 1

Joseph Chong-Sang Wu, Stanford CA

Specialties:
Psychiatry, Internal Medicine, Cardiovascular Disease
Work:
Stanford Hospital and Clinics
300 Pasteur Dr, Stanford, CA 94305
Education:
University of California at Irvine (1982)


Joseph Wu Photo 2

Double-Fusion Human Embryonic Stem Cells, Methods Of Making Double-Fusion Human Embryonic Stem Cells, Triple-Fusion Human Embryonic Stem Cells, Methods Of Making Triple-Fusion Human Embryonic Stem Cells, And Methods Of Monitoring Double-Fusion Human Embryonic Stem Cells And Triple-Fusion Human Embryonic Stem Cells

US Patent:
2009017, Jul 9, 2009
Filed:
Dec 4, 2008
Appl. No.:
12/315873
Inventors:
Joseph Ching-Ming Wu - Palo Alto CA, US
Feng Cao - San Jose CA, US
International Classification:
C12Q 1/66, C12N 5/10, C12N 15/09
US Classification:
435 8, 435346, 435455
Abstract:
Embodiments of the present disclosure include double-fusion human embryonic stem cells, methods of imaging double-fusion human embryonic stem cells, double-fusion polynucleotides, double-fusion proteins, triple-fusion human embryonic stem cells, methods of imaging triple-fusion human embryonic stem cells, triple-fusion polynucleotides, triple-fusion proteins, methods of monitoring the progression of human embryonic stem cells, methods of making isolated double-fusion human embryonic stem cells, methods of making isolated triple-fusion human embryonic stem cells, and the like.


Joseph Wu Photo 3

Double-Fusion Human Embryonic Stem Cells, Method Of Making Double-Fusion Human Embryonic Stem Cells, Triple-Fusion Human Embryonic Stem Cells, Method Of Making Triple-Fusion Human Embryonic Stem Cells, And Methods Of Monitoring Double-Fusion Human Embryonic Stem Cells And Triple-Fusion Human Embryonic Stem Cells

US Patent:
2012014, Jun 7, 2012
Filed:
Jan 26, 2012
Appl. No.:
13/358838
Inventors:
Joseph Ching-Ming Wu - Palo Alto CA, US
Feng Cao - San Jose CA, US
Sanjiv Sam Gambhir - Porollo Valley CA, US
Assignee:
The Board of Trustees of the Leland Stanford Junior University - Palo Alto CA
International Classification:
A61K 49/00, G01N 21/76, A61K 51/02, G01N 21/64
US Classification:
800 3, 435 618, 424 111, 424 96
Abstract:
Embodiments of the present disclosure include double-fusion human embryonic stem cells, methods of imaging double-fusion human embryonic stem cells, double-fusion polynucleotides, double-fusion proteins, triple-fusion human embryonic stem cells, methods of imaging triple-fusion human embryonic stem cells, triple-fusion polynucleotides, triple-fusion proteins, methods of monitoring the progression of human embryonic stem cells, methods of making isolated double-fusion human embryonic stem cells, methods of making isolated triple-fusion human embryonic stem cells, and the like.


Joseph Wu Photo 4

Cardiomyocytes From Induced Pluripotent Stem Cells From Patients And Methods Of Use Thereof

US Patent:
2013002, Jan 31, 2013
Filed:
Jul 20, 2012
Appl. No.:
13/554946
Inventors:
Ning Sun - Stanford CA, US
Michael T. Longaker - Stanford CA, US
Robert C. Robbins - Stanford CA, US
Joseph Wu - Stanford CA, US
Feng Lan - Menlo Park CA, US
Andrew Stephen Lee - Palo Alto CA, US
Paul W. Burridge - Stanford CA, US
International Classification:
C12Q 1/02, G01N 27/49, C40B 30/06, C12N 5/077, C40B 30/04, C40B 40/02, G01N 21/64, C12Q 1/68
US Classification:
506 9, 435 29, 435 612, 435366, 435 71, 435 611, 506 14, 506 10
Abstract:
Human somatic cells obtained from individuals with a genetic heart condition are reprogrammed to become induced pluripotent stem cells (iPS cells), and differentiated into cardiomyocytes for use in analysis, screening programs, and the like.


Joseph Wu Photo 5

Use On Minicircle Vectors For Cardiac Gene Therapy

US Patent:
8445454, May 21, 2013
Filed:
Oct 22, 2010
Appl. No.:
12/925483
Inventors:
Joseph Wu - Palo Alto CA, US
Mark A. Kay - Los Altos CA, US
Mei Huang - Menlo Park CA, US
Zhi-Ying Chen - Foster City CA, US
Assignee:
The Board of Trustees of the Leland Stanford Junior University - Palo Alto CA
International Classification:
A61K 48/00, C07H 21/04, C07H 21/02, C12N 15/63
US Classification:
514 44, 536 231, 536 2431, 536 2433, 536 245, 4353201
Abstract:
Compositions and methods are provided for the treatment of an ischemic cardiovascular condition by providing a patient with a novel non-viral minicircle DNA vector comprising polynucleotide sequences that potentiate HIF-1 activity, including RNAi or antisense agents selective for proteins involved in HIF1 inactivation.


Joseph Wu Photo 6

Enhanced Efficiency Of Induced Pluripotent Stem Cell Generation

US Patent:
2011024, Oct 6, 2011
Filed:
Feb 1, 2011
Appl. No.:
12/931476
Inventors:
Joseph Wu - Palo Alto CA, US
Michael T. Longaker - Stanford CA, US
Mark A. Kay - Stanford CA, US
Ning Sung - Stanford CA, US
FangJun Jia - Stanford CA, US
Zhi-Ying Chen - Shenzhen, CN
Nicholas Panetta - Pittsburg PA, US
Deepak Gupta - Stanford CA, US
International Classification:
C12N 5/074, C12N 15/63
US Classification:
435366, 435377, 4353201
Abstract:
Human somatic cells are reprogrammed to become induced pluripotent stem cells (iPS cells) by the introduction of a minicircle DNA vector. Cells of interest include adipose stem cells.


Joseph Wu Photo 7

Prevention Of Immunological Rejection Of Transplanted Stem Cells By Leukocyte Costimulatory Molecule Blockade

US Patent:
2011029, Dec 1, 2011
Filed:
May 16, 2011
Appl. No.:
13/068643
Inventors:
Jeremy Pearl - San Francisco CA, US
Joseph Wu - Stanford CA, US
Mark Davis - Atherton CA, US
International Classification:
A61K 39/395, A61P 37/06, A61P 25/00, A61K 35/12, A61K 35/30
US Classification:
4241341, 424 937, 4241731
Abstract:
Compositions and methods are provided for transplantation of pluripotent stem cells and differentiated cells derived therefrom.


Joseph Wu Photo 8

Novel Shrna Gene Therapy For Treatment Of Ischemic Heart Disease

US Patent:
2012000, Jan 5, 2012
Filed:
Sep 15, 2009
Appl. No.:
12/998075
Inventors:
Joseph C. Wu - Palo Alto CA, US
Amato John Giaccia - Stanford CA, US
Mei Huang - Palo Alto CA, US
Denise A. Chan - Palo Alto CA, US
Assignee:
The Board of Trustees of the Leland Stanford Junio - Palo Alto CA
International Classification:
A61K 31/7105, A61P 17/02, A61P 7/00, C12N 15/85, A61P 9/10
US Classification:
514 44 R, 4353201
Abstract:
Short hairpin RNA (shRNA) interference therapy targeting hypoxia inducible factor—lot (HIF-1 α) prolyl-4-hydroxylase protein (HIF-PHD2) is used for treatment of myocardial ischemia. This treatment can be followed noninvasively by molecular imaging. Provided are compositions comprising novel vectors encoding shRNA targeting the HIF-1α and asparaginyl hydroxylase genes. The vectors encoding shRNA are also useful for the treatment of cardiac diseases, peripheral vascular diseases and decubitis ulcers.