Inventors:
Ronald Levy - Stanford CA, US
Wen-Kai Weng - Saratoga CA, US
International Classification:
C12Q 1/68, G01N 33/53
Abstract:
Methods and compositions are provided for determining whether a subject suffering from a neoplastic condition is responsive to an antineoplastic therapy, such as antibody therapy, e.g., Rituximab. In practicing the subject methods, the subject is genotyped to determine whether the subject has a least one favorable FcγR polymorphism, e.g., the 131 H/H genotype or the 158 V/V genotype. In addition, reagents, devices and kits thereof, that find use in practicing the subject methods are provided.