Inventors:
David Margulies - Newton MA, US
Joseph Majzoub - Wellesley MA, US
Isaac Kohane - Newton MA, US
Joyce Samet - Brookline MA, US
International Classification:
C12Q001/68, G06F019/00, G01N033/48, G01N033/50
Abstract:
Changes in association between a genetic variant and a disorder can be used as a prompt to automatically revise the diagnosis based on the patient's genetic information. For example, revisions in levels of confidence of a curated database of variants can trigger sending an updated report to the clinician or patient.