Inventors:
Jean Kim - Baltimore MD, US
Assignee:
The Johns Hopkins University - Baltimore MD
International Classification:
A61K 39/395, A61K 38/02, A61K 31/501, C12Q 1/18, A61P 11/00, A61P 29/00, A61P 11/06, C12N 5/071, A61K 31/7088, A61K 31/506
US Classification:
4241331, 4241301, 514 44 R, 514 81, 514 11, 4241581, 4241721, 514 44 A, 51425203, 514275, 435375, 435 32
Abstract:
This invention relates, e.g., to a method for treating a subject having a chronic inflammatory respiratory disorder, comprising administering to the subject an effective amount of an inhibitor of the expression of and/or the activity of VEGF-A and/or VEGFR1 and/or VEGFR2 and/or NP1, or a combination thereof. Also described are screeing assays for agents for treating a subject having a chronic inflammatory respiratory disorder, and kits for performing one of the methods of the invention.