Inventors:
Vann Bennett - Hillsborough NC, US
Jane Healy - Boston MA, US
International Classification:
C12Q 1/68, C12Q 1/54, G06F 17/30, A61K 38/26, A61K 38/17, A61P 3/10, G01N 33/566, C40B 30/04
US Classification:
514 72, 435 611, 435 792, 435 14, 506 9, 514 69, 707769, 707E17014
Abstract:
Loss of function ankyrin-B variants have impaired function in pancreatic islets and are associated with type 2 diabetes. This finding provides the basis for methods of identifying at-risk individuals for type 2 diabetes and for personalized therapeutic strategies.