Inventors:
Rami Burstein - Chestnut Hill MA, US
Catherine Buettner - Boston MA, US
Assignee:
BETH ISRAEL DEACONESS MEDICAL CENTER, INC. - Boston MA
International Classification:
A61K 31/59, A61K 31/593, A61P 25/06, A61P 25/08, A61P 19/02, A61P 1/08, A61P 25/24, A61P 25/22, A61K 31/592, A61P 21/00
Abstract:
The present invention is related to compositions and methods for treating or reducing the likelihood of a migraine, reducing the severity of migraine, reducing the frequency of migraines, reducing the duration of migraine, and ameliorating the symptoms of a migraine. The methods and compositions of the present invention may also be used to treat or prevent condition characterized by increased cardiovascular risk or endothelial dysfunction and musculoskeletal symptoms.