DR. JAMES KAI-CHEN LIU, MD
Medical Practice at Metrohealth Dr, Cleveland, OH

7939098, May 10, 2011

May 22, 2003

10/444634

Giovanni M. Pauletti - Loveland OH, US
James H. Liu - University Heights OH, US
Wolfgang A. Ritschell - Cincinnati OH, US

Femina Pharma Incorporated - Miami FL

A61K 38/00, A61K 38/01

424434, 424443, 424430

Compositions and methods for vaginal, buccal or nasal transmucosal delivery of drugs and for cryoprotecting of cells and embryos. For cryoprotection, the composition consisting essentially consist of a non-ionizable glycol derivative. For transmucosal delivery, the compositions essentially consist of a non-ionizable glycol derivative in a combination with a pharmaceutically active agent. For transmucosal delivery, the non-ionizable glycol derivative may be further combined with a mucoadhesive agent and/or a penetration enhancer and/or lipophilic or hydrophilic carrier for adhesion to and transport through a mucosa. The compositions are particularly suitable for administration of drugs through a nasal, buccal and vaginal mucosa or for long-term preservation of cell or embryos.

2005016, Jul 28, 2005

Mar 16, 2005

11/082367

Steven Gehling - Oshkosh WI, US
Donald Harrison - Indian Hill OH, US
James Liu - Bratenahl OH, US
Wolfgang Ritschel - Cincinnati OH, US
Roger Stern - Sunnyvale CA, US

A61L015/00

424445000, 424404000

A tampon adapted to deliver a therapeutic agent, the tampon including a tampon body that is manufactured at a first manufacturing facility; and a dosage form coupled to the body, wherein the dosage form includes a formulation including a therapeutic agent, and wherein the dosage form is manufactured at a second manufacturing facility. Also, a method for producing a medicated tampon including manufacturing a tampon body at a first manufacturing facility; manufacturing a dosage form at a second manufacturing facility, wherein the dosage form includes a formulation including a therapeutic agent; and coupling the dosage form to the tampon body.

7341737, Mar 11, 2008

Dec 31, 2002

10/335759

Steven Craig Gehling - Oshkosh WI, US
Donald C. Harrison - Indian Hill OH, US
James H. Liu - Bratenahl OH, US
Wolfgang A. Ritschel - Cincinnati OH, US
Chris Clendening - Cleves OH, US
Giovanni M. Pauletti - Loveland OH, US

Kimberly-Clark Worldwide, Inc. - Neenah WI

A61F 13/02, A61F 9/02, A61F 13/20

424431, 424430, 424433, 424436, 424729, 424732, 424744, 424754, 424757, 424767, 514966, 514967, 604358, 604604

A tampon adapted to deliver a therapeutic agent, the tampon including a tampon body having a distal end; and a dosage form affixed to the distal end of the tampon body, wherein the dosage form includes a formulation including a therapeutic agent, and wherein the dosage form comprises a plurality of layers. Also, a method for manufacturing a medicated tampon adapted to deliver a therapeutic agent, the method including manufacturing a tampon body having a distal end; producing a dosage form having a plurality of layers, wherein the dosage form includes a formulation including a therapeutic agent; and affixing the dosage form to the distal end of the tampon body.