Inventors:
Stephen J. Baker - Mountain View CA, US
Tsutomu Akama - Sunnyvale CA, US
Vincent S. Hernandez - Watsonville CA, US
Karin M. Hold - Belmont CA, US
James J. Leyden - Malvern PA, US
Kirk R. Maples - San Jose CA, US
Jacob J. Plattner - Berkeley CA, US
Virginia Sanders - San Francisco CA, US
Yong-Kang Zhang - San Jose CA, US
Assignee:
Anacor Pharmaceuticals, Inc. - Palo Alto CA
International Classification:
A61K 31/69, C07F 5/04
Abstract:
This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.