Inventors:
Agnes Juhasz - Glendora CA, US
James Doroshow - Bethesda MD, US
Susan Markel - Pomona CA, US
Shikha Gaur - Glendora CA, US
International Classification:
A61K 31/7052, A61P 43/00, C07H 21/02, C12N 15/63, C12N 15/85
US Classification:
514044000, 435320100, 435455000, 435466000, 536023100
Abstract:
The present invention relates to compositions and methods for gene-specific inhibition of gene expression by short interfering ribonucleic acid (siRNA) effector molecules. The compositions and methods are particularly useful in modulating gene expression of the NOX1 gene in colon cancer cells.