Inventors:
Kelly N. Owens - Seattle WA, US
Anna L. Corke - Seattle WA, US
Henry C. Ou - Seattle WA, US
Edwin W. Rubel - Seattle WA, US
David W. Raible - Seattle WA, US
Julian A. Simon - Seattle WA, US
Assignee:
University of Washington - Seattle WA
Fred Hutchinson Cancer Research Center - Seattle WA
International Classification:
A61K 33/24, A61K 31/522, A61K 31/122, A61K 31/4965, A61K 31/546, A61K 31/4706, A61K 31/138, A61K 31/438, A61K 31/7036, A61P 17/00, A61P 27/16
US Classification:
424649, 51426334, 514682, 51425506, 514202, 514313, 514651, 514278, 51425216, 514 39
Abstract:
The invention provides compounds, compositions and methods that can be used for the attenuation of damage to sensory hair cells and symptoms thereof. More particularly, the invention identifies drugs that can be used to protect sensory hair cells from ototoxic medications, noise-induced damage and age-related loss.