Inventors:
Karl Erik Hellstrom - Seattle WA, US
Ingegerd Hellstrom - Seattle WA, US
Pu Liu - Rockville MD, US
Jade Jaffar - Camperdown, AU
Elizabeth Swisher - Seattle WA, US
Assignee:
University of Washington through its Center for Commercialization - Seattle WA
International Classification:
G01N 33/68
Abstract:
The present invention features, inter alia, compositions and methods related to the detection of HE4-expressing tumor cells in a subject. The methods include detection of anti-HE4 antibodies in a biological sample obtained from the subject. The methods are useful for diagnosis and monitoring the efficacy of treatments for cancers in which HE4 is expressed, for example, ovarian cancer.