HELENE C VERVOORT
Broker in Kates Corner, MA
License number
Massachusetts 9084423
Issued Date
Nov 22, 2005
Expiration Date
Sep 18, 2008
Type
Salesperson
Address
Address
Kates Corner, MA 01824
Professional information
Screening Of Chemical Compounds Purified From Biological Sources
US Patent:
2008025, Oct 16, 2008
Filed:
Mar 18, 2008
Appl. No.:
12/077256
Inventors:
Gary Eldridge - San Diego CA, US
Lu Zeng - San Diego CA, US
Peader Cremin - San Diego CA, US
Chris Lee - Yorba Linda CA, US
Helene C. Vervoort - Chelmsford MA, US
Marilyn Ghanem - St. Louis MO, US
Lu Zeng - San Diego CA, US
Peader Cremin - San Diego CA, US
Chris Lee - Yorba Linda CA, US
Helene C. Vervoort - Chelmsford MA, US
Marilyn Ghanem - St. Louis MO, US
International Classification:
C40B 30/00, C40B 50/00
US Classification:
506 12, 506 23
Abstract:
A method of producing a chemical compound library comprises extracting at least one extract from at least one species of plant; processing at least one of the extract(s) to remove at least one type of chemical interference to produce a processed extract; chromatographically separating the processed extract into a plurality of chromatographic fractions, each containing an amount of chemical compounds; determining the amount of chemical compounds in at least one of the chromatographic fractions; and normalizing the chromatographic fractions in which the amounts were determined to produce normalized chromatographic fractions, each such fraction comprising from about 1 microgram to about 500 micrograms of each of from one to seven chemical compounds that were present in lower concentrations in the extract and that each have a log P of from about −1 to about 5 and a molecular weight less than about 1000 Daltons; thereby to produce a chemical compound library from at least one species of plant.
Screening Of Chemical Compounds Purified From Biological Sources
US Patent:
7367933, May 6, 2008
Filed:
Feb 21, 2006
Appl. No.:
11/358815
Inventors:
Gary Eldridge - San Diego CA, US
Lu Zeng - San Diego CA, US
Peader Cremin - San Diego CA, US
Chris Lee - Yorba Linda CA, US
Helene C. Vervoort - Chelmsford MA, US
Marilyn Ghanem - St. Louis MO, US
Lu Zeng - San Diego CA, US
Peader Cremin - San Diego CA, US
Chris Lee - Yorba Linda CA, US
Helene C. Vervoort - Chelmsford MA, US
Marilyn Ghanem - St. Louis MO, US
Assignee:
Sequoia Sciences, Inc. - St. Louis MO
International Classification:
C40B 50/00, G01N 33/53
US Classification:
506 23, 435 71
Abstract:
A method of producing a chemical compound library comprises extracting at least one extract from at least one species of plant; processing at least one of the extract(s) to remove at least one type of chemical interference to produce a processed extract; chromatographically separating the processed extract into a plurality of chromatographic fractions, each containing an amount of chemical compounds; determining the amount of chemical compounds in at least one of the chromatographic fractions; and normalizing the chromatographic fractions in which the amounts were determined to produce normalized chromatographic fractions, each such fraction comprising from about 1 microgram to about 500 micrograms of each of from one to seven chemical compounds that were present in lower concentrations in the extract and that each have a log P of from about −1 to about 5 and a molecular weight less than about 1000 Daltons; thereby to produce a chemical compound library from at least one species of plant.