Inventors:
Brian D. Burkinshaw - Pflugerville TX, US
Steven I. Whitlock - Austin TX, US
James B. Rogan - Austin TX, US
Gerald L. Devries - Austin TX, US
International Classification:
A61K 38/36, A61K 39/395, A61K 38/21, A61K 9/127, A61P 7/04, A61P 29/00, A61P 23/00, A61P 31/00, A61P 7/02, A61P 31/10, A61P 9/00, A61P 35/00, A61P 19/08, A61P 19/04, A61P 3/02, A61K 35/58
US Classification:
424450, 514 136, 424542, 4241301, 424 854
Abstract:
The invention includes a composition useful for preparing a tissue sealant for use on a patient, comprising: autologous fibrinogen, an activating agent and at least one supplement. The invention includes a method of treating a disc having at least one defect, comprising: introducing a composition into the disc, wherein the composition comprises autologous fibrinogen and an activating agent, and wherein the composition forms fibrin.