Inventors:
Lisa Jennings - Memphis TN, US
Celia Longhurst - Memphis TN, US
George Cook - Bartlett TN, US
Jianxong Bao - Shawnee Mission KS, US
Chunxiang Zhang - Memphis TN, US
Melanie White - Memphis TN, US
Joseph Crossno - Littleton CO, US
Yi Lu - Cordova TN, US
International Classification:
A61K039/395
Abstract:
Polypeptide and peptide fragments of CD9 as well as antibodies raised against those fragments of CD9. Uses of polypeptide and peptide fragments of CD9, antibodies, and inhibitors of CD9-related kinases include modifying cell behavior such as adhesion, motility, proliferation, survival, cell spreading, invasiveness, pericellular FN matrix assembly, and cell-to-cell interaction.