EUAN A ASHLEY, MBCHB
Osteopathic Medicine at Pasteur Dr, Palo Alto, CA
License number
California A93502
Category
Osteopathic Medicine
Type
Cardiovascular Disease
Address
Address
300 Pasteur Dr, Palo Alto, CA 94305
Phone
(650) 498-5710
Professional information
Dr. Euan Ashley - MD (Doctor of Medicine)
Hospitals:
Stanford Office
300 Pasteur Dr STE A260, Stanford 94305
Stanford Hospital and Clinics
300 Pasteur Dr, Stanford 94305
Stanford Office
300 Pasteur Dr STE A260, Stanford 94305
Stanford Hospital and Clinics
300 Pasteur Dr, Stanford 94305
300 Pasteur Dr STE A260, Stanford 94305
Stanford Hospital and Clinics
300 Pasteur Dr, Stanford 94305
Stanford Office
300 Pasteur Dr STE A260, Stanford 94305
Stanford Hospital and Clinics
300 Pasteur Dr, Stanford 94305
Euan Angus Ashley, Stanford CA
Specialties:
Cardiologist
Address:
300 Pasteur Dr, Stanford, CA 94305
Diagnostic Markers And Pharmacological Targets In Heart Failure And Related Reagents And Methods Of Use Thereof
US Patent:
2005015, Jul 14, 2005
Filed:
May 21, 2004
Appl. No.:
10/850941
Inventors:
Euan Ashley - Palo Alto CA, US
Mary Chen - Fremont CA, US
Thomas Quertermous - Stanford CA, US
David Xing-Fei Deng - Mountain View CA, US
Anya Tsalenko - Chicago IL, US
Amir Ben-dor - Bellevue WA, US
Laurakay Bruhn - Mountain View CA, US
Zohar Yakhini - Ramat HaSharon, IL
Mary Chen - Fremont CA, US
Thomas Quertermous - Stanford CA, US
David Xing-Fei Deng - Mountain View CA, US
Anya Tsalenko - Chicago IL, US
Amir Ben-dor - Bellevue WA, US
Laurakay Bruhn - Mountain View CA, US
Zohar Yakhini - Ramat HaSharon, IL
International Classification:
A61K051/00, C12Q001/68, G01N033/53, G01N033/567, C07K016/46
US Classification:
424001490, 435006000, 435007200, 530391100
Abstract:
The invention identifies genes whose expression is upregulated or downregulated following mechanical offloading in subjects with heart failure. The invention provides compositions comprising a targeting agent conjugated to a functional moiety, wherein the targeting agent selectively binds to a polypeptide encoded by one of these genes. The functional moiety can be an imaging agent, therapeutic agent, etc. The invention further provides methods for providing diagnostic or prognostic information related to heart failure involving detecting expression or activity of an expression product of one or more of the identified genes. The invention further provides diagnostic and therapeutic methods comprising detecting or administering an apelin peptide to a subject.