Inventors:
Napoleone Ferrara - San Francisco CA
Kathleen King - Pacifica CA
Elizabeth Luis - San Francisco CA
Jennie P. Mather - Millbrae CA
Nicholas F. Paoni - Belmont CA
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
A61K 3817
US Classification:
514 21, 514 2, 530300, 530350
Abstract:
A leukemia inhibitory factor antagonist, alone or in combination with an endothelin antagonist, may be used for treatment of heart failure. The antagonist(s) are administered in a chronic fashion, in therapeutically effective amounts, to achieve this purpose.