Inventors:
Alan Horsager - Los Angeles CA, US
Kenneth Greenberg - Oakland CA, US
Benjamin C. Matteo - San Francisco CA, US
Edward S. Boyden - Chestnut MA, US
Douglas G. Ririe - Winston-Salem NC, US
James C. Eisenach - Winston-Salem NC, US
Christian Wentz - Cambridge MA, US
International Classification:
A61K 41/00, A61N 5/06
US Classification:
514 44 R, 536 231, 536 237, 4352351, 435325, 4353201, 435455, 604 20
Abstract:
The present invention provides compositions and methods for the selective silencing of neurons in pain pathway by using a combination of inhibitory light-sensitive protein gene transfer and wavelength specific illumination.