DONALD E MACFARLANE, MD
Osteopathic Medicine at Hawkins Dr, Iowa City, IA
License number
Iowa 22247
Category
Osteopathic Medicine
Type
Internal Medicine
License number
Iowa 22247
Category
Osteopathic Medicine
Type
Hematology & Oncology
Address
Address
200 Hawkins Dr, Iowa City, IA 52242
Phone
(319) 356-2527
(319) 353-8383 (Fax)
(319) 353-8383 (Fax)
Organization information
See more information about DONALD E MACFARLANE at bizstanding.comUniversity Of Iowa Hosps CLNCS - Donald E Macfarlane MD
200 Hawkins Dr #5970JPP, Iowa City, IA 52242
Categories:
Hematology Physicians & Surgeons
Phone:
(319) 356-2527 (Phone)
Professional information
Owner, Lexeme Technology
Location:
Iowa City, Iowa Area
Industry:
Information Technology and Services
Dr. Donald E Macfarlane, Iowa City IA - MD (Doctor of Medicine)
Specialties:
Hematology
Address:
UNIVERSITY OF IOWA HOSP MEDICINE SPECIALTIES CLINIC
200 Hawkins Dr, Iowa City 52242
(319) 356-1616 (Phone), (319) 356-7893 (Fax)
University Iowa Hosp Hmtlgy Onc
200 Hawkins Dr STE 5970, Iowa City 52242
(319) 356-2527 (Phone)
200 Hawkins Dr, Iowa City 52242
(319) 356-1616 (Phone), (319) 356-7893 (Fax)
University Iowa Hosp Hmtlgy Onc
200 Hawkins Dr STE 5970, Iowa City 52242
(319) 356-2527 (Phone)
Languages:
English
Hospitals:
UNIVERSITY OF IOWA HOSP MEDICINE SPECIALTIES CLINIC
200 Hawkins Dr, Iowa City 52242
University Iowa Hosp Hmtlgy Onc
200 Hawkins Dr STE 5970, Iowa City 52242
University of Iowa Hospital and Clinics
200 Hawkins Dr, Iowa City 52242
200 Hawkins Dr, Iowa City 52242
University Iowa Hosp Hmtlgy Onc
200 Hawkins Dr STE 5970, Iowa City 52242
University of Iowa Hospital and Clinics
200 Hawkins Dr, Iowa City 52242
Education:
Residency Hospital
University Iowa Hosps and Clinics
University Iowa Hosps and Clinics
Methods For Inhibiting Immunostimulatory Dna Associated Responses
US Patent:
6521637, Feb 18, 2003
Filed:
Apr 2, 2002
Appl. No.:
10/115421
Inventors:
Donald E. Macfarlane - Iowa City IA
Assignee:
University of Iowa Research Foundation - Iowa City IA
International Classification:
A61K 3147
US Classification:
514313, 514312, 514298
Abstract:
The invention features methods for inhibiting immunostimulatory DNA-associated immune responses, through the administration of specific compounds of the general class of 9-aminoacridines and 4-aminoquiniolines. The invention also features methods of screening compounds useful in inhibiting immunostimulatory DNA-induced immune responses.
Antagonism Of Immunostimulatory Cpg-Oligonucleotides By 4-Aminoquinolines And Other Weak Bases
US Patent:
6479504, Nov 12, 2002
Filed:
Jun 16, 2000
Appl. No.:
09/595875
Inventors:
Donald E. Macfarlane - Iowa City IA
Lucjan Strekowski - Stone Mountain GA
Lori Manzel - Cedar Rapids IA
Fyaz M. D. Ismail - Stockton on Tees, GB
Gordon B. Barlin - Turner, AU
Lucjan Strekowski - Stone Mountain GA
Lori Manzel - Cedar Rapids IA
Fyaz M. D. Ismail - Stockton on Tees, GB
Gordon B. Barlin - Turner, AU
Assignee:
The University of Iowa Research Foundation - Iowa City IA
Georgia State University Research Foundation, Inc. - Atlanta GA
The United States of America as represented by the Department of Veterans Affairs - Washington DC
Georgia State University Research Foundation, Inc. - Atlanta GA
The United States of America as represented by the Department of Veterans Affairs - Washington DC
International Classification:
A61K 3144
US Classification:
514297, 514312, 514313, 546105, 546159, 546160
Abstract:
The present invention relates generally to the field of immunology. More particularly it concerns compositions and methods for inhibiting stimulation of the immune system. The compounds and methods comprise compounds that are analogs and derivatives of chloroquine, such as 4-aminoquinolines, and other weak bases. They can be used in preventative and therapeutic treatments of autoimmune diseases and phenomena, transplant rejection such as host-versus-graft disease, and sepsis.
Methods For Inhibiting Immunostimulatory Dna Associated Responses
US Patent:
6399630, Jun 4, 2002
Filed:
Jan 23, 2001
Appl. No.:
09/768874
Inventors:
Donald E. Macfarlane - Iowa City IA
Assignee:
University of Iowa Research Foundation - Aimes IA
International Classification:
A61K 3147
US Classification:
514313, 514312, 514298
Abstract:
The invention features methods for inhibiting immunostimulatory DNA-associated immune responses, through the administration of specific compounds of the general class of 9-aminoacridines and 4-aminoquinolines. The invention also features methods of screening compounds useful in inhibiting immunostimulatory DNA-induced immune responses.
Donald E Macfarlane, Iowa City IA
Specialties:
Internist
Address:
200 Hawkins Dr, Iowa City, IA 52242
Quaternary Amine Surfactants And Methods Of Using Same In Isolation Of Nucleic Acids
US Patent:
5300635, Apr 5, 1994
Filed:
Feb 1, 1993
Appl. No.:
8/013419
Inventors:
Donald E. Macfarlane - Iowa City IA
Assignee:
University of Iowa Research Foundation - Iowa City IA
International Classification:
C07H 2100
US Classification:
536 254
Abstract:
The present invention discloses a novel method for isolating nucleic acids from biological samples, most particularly blood, using selected quaternary amine surfactants. The nucleic acids are isolated quickly and in sufficient quantity and quality to permit analysis by methods including reverse transcriptase and polymerase chain reaction.
Methods For Inhibiting Immunostimulatory Dna Associated Responses
US Patent:
6221882, Apr 24, 2001
Filed:
Jul 2, 1998
Appl. No.:
9/109513
Inventors:
Donald E. Macfarlane - Iowa City IA
Assignee:
University of Iowa Research Foundation - Iowa City IA
International Classification:
A01N 4342
US Classification:
514313
Abstract:
The invention features methods for inhibiting immunostimulatory DNA-associated immune responses, through the administration of specific compounds of the general class of 9-aminoacridines and 4-aminoquiniolines. The invention also features methods of screening compounds useful in inhibiting immunostimulatory DNA-induced immune responses.
Process For Purifying Dna And Rna Using Cationic Detergents
US Patent:
5010183, Apr 23, 1991
Filed:
Jul 7, 1989
Appl. No.:
7/376709
Inventors:
Donald E. Macfarlane - Iowa City IA
International Classification:
C07H 2100, C07H 2102, C07H 2104
US Classification:
536 27
Abstract:
A novel method is provided for purifying DNA and RNA from a variety of sources, including cells, cell lysates, viruses, tissues, blood and other body fluids employing a cationic detergent to complex with the nucleic acids.
Quaternary Amine Surfactants And Methods Of Using Same In Isolation Of Rna
US Patent:
5728822, Mar 17, 1998
Filed:
Sep 7, 1995
Appl. No.:
8/525818
Inventors:
Donald E. Macfarlane - Iowa City IA
Assignee:
Qiagen N.V. - Amsterdam
International Classification:
C07H 2100
US Classification:
536 2541
Abstract:
The present invention discloses a novel method for isolating RNA from biological samples, most particularly blood, using selected quaternary amine surfactants. The RNA is isolated quickly and in sufficient quantity and quality to permit analysis by methods including reverse transcriptase and polymerase chain reaction.